NLRP3 inflammasome in atherosclerosis: putting out the fire of inflammation

…, HY Xu, YC Zhao, XR Zheng, F Wang, GR Zhao - Inflammation, 2023 - Springer
Atherosclerosis (AS) is a chronic inflammatory disease with thickening or hardening of the
arteries, which led to the built-up of plaques in the inner lining of an artery. Among all the …

[HTML][HTML] Smart pH-sensitive nanoassemblies with cleavable PEGylation for tumor targeted drug delivery

G Zhao, L Long, L Zhang, M Peng, T Cui, X Wen… - Scientific reports, 2017 - nature.com
A new acidly sensitive PEGylated polyethylenimine linked by Schiff base (PEG-s-PEI) was
designed to render pH-sensitive PEGylation nanoassemblies through multiple interactions …

[HTML][HTML] T cells, NK cells, and tumor-associated macrophages in cancer immunotherapy and the current state of the art of drug delivery systems

…, Y Ma, Y Wang, Y Zhang, S Yang, G Zhao… - Frontiers in …, 2023 - frontiersin.org
The immune system provides full protection for the body by specifically identifying ‘self’ and
removing ‘others’; thus protecting the body from diseases. The immune system includes …

[HTML][HTML] Analysis of influencing factors on the plasma concentration of first-line anti-tuberculosis drugs-a single-center retrospective cohort study

G Zhao, M Chen, L Sun, N Xi - Annals of translational medicine, 2022 - ncbi.nlm.nih.gov
Background The four most commonly used first-line anti-tuberculosis (TB) drugs in clinical
practice are isoniazid (INH), rifampicin (RFP), ethambutol (EMB), and pyrazinamide (PZA). …

Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells

M Wu, G Zhao, X Zhuang, T Zhang, C Zhang… - OncoTargets and …, 2018 - Taylor & Francis
Background Triclosan is a widely applied antimicrobial agent which affects the endocrine
system and homeostasis; it may also promote the cirrhosis and hepatocellular carcinoma (HCC…

Computer-assisted engineering of programmed drug releasing multilayer nanomedicine via indomethacin-mediated ternary complex for therapy against a multidrug …

…, C Xu, C Zhang, J Meng, J Zheng, H Yuan, G Zhao… - Acta biomaterialia, 2019 - Elsevier
Nanomedicine with programmed drug release can give full play to the synergistic effect of
multi-component system in complicated tumor environment. However, the construction of …

[HTML][HTML] Combining bioinformatics and biological detection to identify novel biomarkers for diagnosis and prognosis of pulmonary tuberculosis

G Zhao, X Luo, X Han, Z Liu - Saudi Medical Journal, 2020 - ncbi.nlm.nih.gov
Objectives: To identify the novel and promising indicators for pulmonary tuberculosis (PTB)
patients Methods: The study was carried out between June 2016 and June 2019. Three RNA …

ING5 inhibits lung cancer invasion and epithelial–mesenchymal transition by inhibiting the WNT/β‐catenin pathway

…, XT Zhang, XH Liang, F Zhang, GR Zhao… - Thoracic …, 2019 - Wiley Online Library
Background ING5 is the last member of the Inhibitor of Growth (ING) candidate tumor
suppressor family that has been implicated in multiple cellular functions, including cell cycle …

Comparison of efficacy and safety between benidipine and hydrochlorothiazide in fosinopril-treated hypertensive patients with chronic kidney disease: protocol for a …

…, C Zhou, B Yang, J Lv, B Dai, S Yu, Y Wang, G Zhao… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Co-administration of a diuretic or calcium channel blocker with an ACE inhibitor
are both preferred combinations in patients with hypertensive chronic kidney disease (CKD)…

[HTML][HTML] Neutrophil extracellular traps in central nervous system (CNS) diseases

BZ Shao, JJ Jiang, YC Zhao, XR Zheng, N Xi, GR Zhao… - PeerJ, 2024 - peerj.com
Excessive induction of inflammatory and immune responses is widely considered as one of
vital factors contributing to the pathogenesis and progression of central nervous system (CNS…