There are 3 main classes of systemic antifungals: the polyene macrolides (eg amphotericin
B), the azoles (eg the imidazoles ketoconazole and miconazole and the triazoles …

Background and aim The occurrence of drug induced liver injury (DILI) is the most common
reason of post-marketing withdrawals. DILI in humans is difficult to predict using in vitro …

In an era when the number of expedited and conditional review pathways for newly available
brand-name drugs and biosimilar medicines to treat serious and life-threatening diseases …

The effects of hydrocortisone, triamcinolone, prednisolone and dexamethasone have been
investigated in vitro using mitochondria isolated from rat brain. Respiratory control ratio (RCR)…

In the recent past, concerns have raised regarding the potential risk of acute pancreatitis
among type 2 diabetic patients using incretin-based drugs such as glucagon-like peptide 1 (GLP…

The pandemic infection by coronavirus 2019 (COVID-19) that spreading from China is generating
a tremendous flow of information and one emerging point is the frequent association of …

The collection and assessment of individual case safety reports (ICSRs) is important to
detect unknown adverse drug reactions particularly in the first decade after approval of new …

Objective. Psoriasis could be a paradoxical reaction to tumor necrosis factor-α antagonist
therapy and it has been reported with rituximab therapy. Our objective was to assess the rates …

Background The use of immune checkpoint inhibitors (ICI) in melanoma and non-small cell
lung cancer patients is associated with the onset of vitiligo. However, previous studies have …

L’objet de cette Table Ronde était de faire un premier état des lieux sur l’impact des médicaments
sur l’environnement. La croissance démographique dans le monde, la demande de …