User profiles for Iruni R. Abeysekera

Iruni Roshanie Abeysekera

NSW Health
Verified email at health.nsw.gov.au
Cited by 221

[HTML][HTML] High serum uric acid levels may increase mortality and major adverse cardiovascular events in patients with acute myocardial infarction

Q Xu, M Zhang, IR Abeysekera, X Wang - Saudi Medical Journal, 2017 - ncbi.nlm.nih.gov
Objectives: To determine the validity of uric acid as a potential prognostic marker for long-term
outcomes of patients with acute myocardial infarction (AMI) and those with AMI …

NKCC1 promotes EMT‐like process in GBM via RhoA and Rac1 signaling pathways

…, L Hai, L Tong, L Yi, IR Abeysekera… - Journal of cellular …, 2019 - Wiley Online Library
Glioblastoma is the most common and lethal primary intracranial tumor. As the key regulator
of tumor cell volume, sodium‐potassium‐chloride cotransporter 1 (NKCC1) expression …

Comparing the risk of cardiovascular disease following GnRH agonist and GnRH antagonist therapy for patient with prostate cancer: a systematic review and meta …

C Ma, IR Abeysekera, W Xu, Y Wang… - Minerva Urology and …, 2020 - europepmc.org
Comparing the risk of cardiovascular disease following GnRH agonist and GnRH
antagonist therapy for patient with prostate cancer: a systematic review and meta-analysis …

[HTML][HTML] The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion

…, L Hai, H Ma, Z Tao, C Zhang, IR Abeysekera… - Cell Death & …, 2018 - nature.com
Numerous studies have shown that calmodulin (CaM) is a major regulator of calcium-dependent
signaling, which regulates cell proliferation, programmed cell death, and autophagy in …

[HTML][HTML] Tumour cell dormancy as a contributor to the reduced survival of GBM patients who received standard therapy

L Tong, L Yi, P Liu, IR Abeysekera… - Oncology …, 2018 - spandidos-publications.com
Glioblastoma multiforme (GBM) is a fatal cancer with varying life expectancy, even for patients
undergoing the same standard therapy. Identification of differentially expressed genes in …

Activation of the Nrf2‐Keap 1 Pathway in Short‐Term Iodide Excess in Thyroid in Rats

T Wang, X Liang, IR Abeysekera, U Iqbal… - Oxidative Medicine …, 2017 - Wiley Online Library
… Blood samples were taken from the carotid artery and then centrifuged for 10 min at 2000
r/min to obtain the samples of the serum. After that, the samples were stored at −80C for further …

[HTML][HTML] Jagged1 is clinically prognostic and promotes invasion of glioma-initiating cells by activating NF-κB (p65) signaling

…, S Yu, L Yi, Z Tao, C Zhang, IR Abeysekera… - Cellular Physiology and …, 2019 - karger.com
Background/Aims: Jagged1 is the ligands of the Notch signaling and has been shown to
promote glioma-initiating cells (GICs) in glioblastoma. The role of Jagged1 in GICs invasion and …

GDF11 is increased in patients with aplastic anemia

X Dong, Y Han, IR Abeysekera, Z Shao, H Wang - Hematology, 2019 - Taylor & Francis
Object: To explore the critical role of growth differentiation factor 11 (GDF11) in the pathobiology
of aplastic anemia (AA). Methods: We have examined the serum GDF11 levels for 79 …

[HTML][HTML] Bioinformatic analyses reveal the key pathways and genes in the CXCR4 mediated mesenchymal subtype of glioblastoma

…, L Tong, T Li, L Hai, IR Abeysekera… - Molecular …, 2018 - spandidos-publications.com
Glioblastoma multiforme (GBM) is one of the most lethal types of tumour, despite severe
treatment methods. The Cancer Genome Atlas has categorised GBMs into proneural, neural, …

[HTML][HTML] Propylthiouracil, perchlorate, and thyroid-stimulating hormone modulate high concentrations of iodide instigated mitochondrial superoxide production in the …

…, V Perera, X Liang, IR Abeysekera… - Endocrinology and …, 2016 - ncbi.nlm.nih.gov
Background Increased oxidative stress has been suggested as one of the underlying
mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as …