[HTML][HTML] The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes

…, Z Kang, H Gong, D Xu, J Wang, Z Li, X Cui, J Xiao… - BioRxiv, 2020 - biorxiv.org
Since December 2019, a newly identified coronavirus (2019 novel coronavirus, 2019-nCov)
is causing outbreak of pneumonia in one of largest cities, Wuhan, in Hubei province of …

Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

…, H Gong, D Xu, J Wang, Z Li, Z Li, X Cui, J Xiao… - Gut, 2020 - gut.bmj.com
Objective Since December 2019, a newly identified coronavirus (severe acute respiratory
syndrome coronavirus (SARS-CoV-2)) has caused outbreaks of pneumonia in Wuhan, China. …

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption

…, D Li, S Siwko, JM Penninger, G Ning, J Xiao… - Nature medicine, 2016 - nature.com
Tumor necrosis factor (TNF) superfamily member 11 (TNFSF11, also known as RANKL)
regulates multiple physiological or pathological functions, including osteoclast differentiation …

Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation

X Wang, J Zhang, Y Wang, C Wang, J Xiao, Q Zhang… - Biomaterials, 2016 - Elsevier
Photothermal-chemotherapy (PT-CT) is a promising strategy for cancer treatment, but its
development is hindered by the issues regarding to the long-term safety of carriers and …

Glutathione-triggered “off–on” release of anticancer drugs from dendrimer-encapsulated gold nanoparticles

…, J Hu, N Shao, F Wang, Q Zhang, J Xiao… - Journal of the …, 2013 - ACS Publications
Polymeric nanoparticles that can stably load anticancer drugs and release them in response
to a specific trigger such as glutathione are of great interest in cancer therapy. In the present …

Stimuli-responsive dendrimers in drug delivery

H Wang, Q Huang, H Chang, J Xiao, Y Cheng - Biomaterials science, 2016 - pubs.rsc.org
Dendrimers have shown great promise as carriers in drug delivery due to their unique
structures and superior properties. However, the precise control of payload release from a …

Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges

X Gao, L Li, X Cai, Q Huang, J Xiao, Y Cheng - Biomaterials, 2021 - Elsevier
A variety of targeted nanoparticles were developed for the diagnosis and therapy of orthotopic
and metastatic bone tumors during the past decade. This critical review will focus on …

Platelet-to-lymphocyte ratio in advanced cancer: review and meta-analysis

BO Li, P Zhou, Y Liu, H Wei, X Yang, T Chen, J Xiao - Clinica Chimica Acta, 2018 - Elsevier
Background Inflammation biomarkers have been introduced into clinical practice for risk-rating
in treatment of patients with cancer. We aimed to confirm the prognostic role of platelet-to-…

[HTML][HTML] HIF1/2α mediates hypoxia-induced LDHA expression in human pancreatic cancer cells

…, DW Song, W Yan, XH Yang, T Liu, H Wei, J Xiao - Oncotarget, 2017 - ncbi.nlm.nih.gov
Glycolysis is a typical conduit for energy metabolism in pancreatic cancer (PC) due to the
hypoxic microenviroment. Lactate dehydrogenase A (LDHA) catalyzes the conversion of …

Fluorinated poly (propylenimine) dendrimers as gene vectors

H Liu, Y Wang, M Wang, J Xiao, Y Cheng - Biomaterials, 2014 - Elsevier
The use of poly(propylenimine) (PPI) dendrimers as gene delivery vectors is limited by their
low transfection efficacy and serious cytotoxicity. In this study, we prepare a series of efficient …