Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …

Despite the massive advancements in the nanomedicines and their associated research,
their translation into clinically-applicable products is still below promises. The latter fact …

Hepatocellular carcinoma (HCC) is a fatal disease with limited therapeutic choices. The
stroma-rich tumor microenvironment hinders the in vivo delivery of most nanomedicines. Ultra-…

Hepatocellular carcinoma (HCC), a common deadly malignancy, requires novel therapeutic
strategies to improve the survival rate. Combining chemotherapy and gene therapy is a …

The adverse effects of either NaCl or mannitol on growth, nitrogen content, and antioxidant
system in Vicia faba seedlings were investigated. The role of exogenous ascorbic acid in …

A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …

Herein, we report on the development of a platform for the selective delivery of mRNA to the
hard-to-transfect Activated Hepatic Stellate Cells (aHSCs), the fundamental player in the …

We report on a novel strategy for treating liver fibrosis through reprogramming activated
Hepatic Stellate Cells (aHSCs) into quiescent Hepatic Stellate Cells (qHSCs) using siRNA-…

Throughout decades, the intrinsic power of the immune system to fight pathogens has inspired
researchers to develop techniques that enable the prevention or treatment of infections …

Sulpiride (SUL), anti-dopaminergic drug, has a specific site for absorption located in the
upper portion of the gastrointestinal tract hence, its oral delivery represents a challenge …