Antioxidant and tissue-protective studies on Ajwa extract: dates from Al Madinah Al-Monwarah, Saudia Arabia
AR Ragab, MA Elkablawy, BY Sheik… - J Environ Anal …, 2013 - platform.almanhal.com
The objective was to study the in-vivo protective effect of Al-Madinah Ajwa dates extract
against lead acetate toxicity on the tissues of vital organs. Four rabbit groups were used as an …
against lead acetate toxicity on the tissues of vital organs. Four rabbit groups were used as an …
Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity
HM Abo-Haded, MA Elkablawy, Z Al-Johani… - PLoS one, 2017 - journals.plos.org
Sitagliptin is selective dipeptidyl peptidase-4 inhibitor (DPP4-I), used clinically as a new oral
anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective …
anti-diabetic agent. This study explored the underlying mechanisms of the hepatoprotective …
Pristimerin protects against doxorubicin-induced cardiotoxicity and fibrosis through modulation of Nrf2 and MAPK/NF-kB signaling pathways
…, S Khoshhal, N Ahmed, MA Elkablawy… - Cancer management …, 2018 - Taylor & Francis
Background/purpose Pristimerin (Pris) is triterpenoid compound with many biological effects.
Until now, nothing is known about its effect on doxorubicin (DOX)-induced cardiotoxicity. …
Until now, nothing is known about its effect on doxorubicin (DOX)-induced cardiotoxicity. …
[HTML][HTML] Ki67 expression in breast cancer: Correlation with prognostic markers and clinicopathological parameters in Saudi patients
MA Elkablawy, AM Albasri, RA Mohammed… - Saudi medical …, 2016 - ncbi.nlm.nih.gov
Objectives: To evaluate Ki67 immunoexpression pattern in Saudi breast cancer (BC) patients
and investigate any possible predictive or prognostic value for Ki67. Methods: This is a …
and investigate any possible predictive or prognostic value for Ki67. Methods: This is a …
Cardioprotective effects of sitagliptin against doxorubicin-induced cardiotoxicity in rats
…, HM Abo-Haded, MA Elkablawy - … biology and medicine, 2016 - journals.sagepub.com
There is a large body of evidence suggesting that inhibitors of dipeptidyl peptidase-4, such
as sitagliptin, may exhibit beneficial effects against different inflammatory disorders. This …
as sitagliptin, may exhibit beneficial effects against different inflammatory disorders. This …
Montelukast, a leukotriene receptor antagonist abrogates lipopolysaccharide-induced toxicity and oxidative stress in rat liver
AM Mohamadin, AA Elberry, MA Elkablawy… - Pathophysiology, 2011 - Elsevier
Endotoxemia-induced hepatotoxicity is characterized by disturbed intracellular redox
balance, excessive reactive oxygen species (ROS) generation inducing DNA, proteins and …
balance, excessive reactive oxygen species (ROS) generation inducing DNA, proteins and …
[HTML][HTML] Prognostic significance of Cyclin D1 over-expression in colorectal cancer: an experience from Madinah, Saudi Arabia
AM Albasri, MA Elkablawy, IA Ansari… - Asian Pacific Journal of …, 2019 - ncbi.nlm.nih.gov
Results: Cyclin D1 over-expression was absent in normal mucosa, while 15% cases of
adenoma showed its over-expression. In CRC, Cyclin D1 was expressed at high levels in 24.1% …
adenoma showed its over-expression. In CRC, Cyclin D1 was expressed at high levels in 24.1% …
Modulation of cyclophosphamide-induced cardiotoxicity by methyl palmitate
DS El-Agamy, MA Elkablawy… - Cancer chemotherapy and …, 2017 - Springer
Purpose Cyclophosphamide (CP) is a frequently used anticancer and immunosuppressant
although its use has been associated with severe cardiotoxicity. The present study examined …
although its use has been associated with severe cardiotoxicity. The present study examined …
Lutein mitigates cyclophosphamide induced lung and liver injury via NF-κB/MAPK dependent mechanism
AA El-Kholy, MA Elkablawy, DS El-Agamy - Biomedicine & …, 2017 - Elsevier
This study targeted to test the potential protective role of lutein against lung and liver damage
associated with cyclophosphamide (CP) administration. Lutein was given orally for 5 days …
associated with cyclophosphamide (CP) administration. Lutein was given orally for 5 days …
Protective activity of tovophyllin A, a xanthone isolated from Garcinia mangostana pericarps, against acetaminophen-induced liver damage: role of Nrf2 activation
…, N Ahmed, MA Elkablawy, GA Mohamed - Food & Function, 2018 - pubs.rsc.org
Garcinia mangostana L. (GM, family Guttiferae) is one of the most widely recognized tropical
fruits. GM is a wealthy pool of xanthones that exhibit a wide range of bioactivities. …
fruits. GM is a wealthy pool of xanthones that exhibit a wide range of bioactivities. …