Rutin protects dopaminergic neurons from oxidative stress in an animal model of Parkinson's disease
This study was undertaken to investigate the neuroprotective effects of rutin (vitamin P) on 6-hydroxydopamine
(6-OHDA)-induced Parkinson’s disease (PD) in rats. Oxidative stress and …
(6-OHDA)-induced Parkinson’s disease (PD) in rats. Oxidative stress and …
Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat …
…, F Islam, M Saeed Siddiqui, MM Safhi… - Molecular and cellular …, 2012 - Springer
The pathophysiological mechanisms leading to neuronal injury in middle cerebral artery
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the bases of …
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the bases of …
[HTML][HTML] Vaccine adjuvants–current status and prospects on controlled release adjuvancity
SM Sivakumar, MM Safhi, M Kannadasan… - Saudi Pharmaceutical …, 2011 - Elsevier
The strategy of World Health Organization is to develop efficient and inexpensive vaccine
against various infectious diseases amongst children’s population. Vaccination is considered …
against various infectious diseases amongst children’s population. Vaccination is considered …
Anti-apoptotic and anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's rat model
In the present study, we examined the molecular mechanism by which Piperine (bioactive
compound of Piper nigrum) inhibits neuronal cell apoptosis. We further investigated the anti-…
compound of Piper nigrum) inhibits neuronal cell apoptosis. We further investigated the anti-…
S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia …
…, R Tabassum, MS Siddiqui, OM El-Agnaf, MM Safhi… - Brain research, 2011 - Elsevier
S-allyl cysteine (SAC), a sulfur containing amino acid derived from garlic, has been reported
to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was …
to have antioxidant, anti-cancer, antihepatotoxic and neurotrophic activity. This study was …
Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke
…, R Tabassum, H Javed, MS Siddiqui, MM Safhi… - Brain Research, 2011 - Elsevier
Incidence of stroke is considered to be a major cause of death throughout the world. The
middle cerebral artery occlusion (MCAO) for 2h followed by 22h of reperfusion model was used …
middle cerebral artery occlusion (MCAO) for 2h followed by 22h of reperfusion model was used …
Quercetin protects against oxidative stress associated damages in a rat model of transient focal cerebral ischemia and reperfusion
Experimental studies have demonstrated that oxidative stress and apoptosis play an important
role in cerebral ischemic pathogenesis and may represent a target for treatment. The …
role in cerebral ischemic pathogenesis and may represent a target for treatment. The …
Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
…, R Tabassum, M Ashafaq, F Islam, MM Safhi… - Neurochemistry …, 2013 - Elsevier
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in cognitive
decline and enhancement of oxidative loads in the brain. Flavonoids have been considered …
decline and enhancement of oxidative loads in the brain. Flavonoids have been considered …
Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment …
…, A Khan, R Tabassum, F Islam, MM Safhi… - Journal of the …, 2015 - Elsevier
Recent attention is given to the influence of dietary supplementation on health and mental
well-being. Oxidative stress is associated with many diseases including neurodegenerative …
well-being. Oxidative stress is associated with many diseases including neurodegenerative …
Silymarin protects neurons from oxidative stress associated damages in focal cerebral ischemia: a behavioral, biochemical and immunohistological study in Wistar …
…, G Khuwaja, A Khan, MS Siddiqui, MM Safhi… - Journal of the …, 2011 - Elsevier
Cerebral stroke is the third largest cause of death and the severe leading cause of disability,
thus have astronomical financial and social burden worldwide. Accumulated evidence …
thus have astronomical financial and social burden worldwide. Accumulated evidence …