Role of transforming growth factor–β in airway remodeling in asthma
R Halwani, S Al-Muhsen, H Al-Jahdali… - American journal of …, 2011 - atsjournals.org
TGF-β is one of the main mediators involved in tissue remodeling in the asthmatic lung. This
profibrotic cytokine is produced by a number of cells, including macrophages, epithelial cells…
profibrotic cytokine is produced by a number of cells, including macrophages, epithelial cells…
Remodeling in asthma
S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
[HTML][HTML] Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization
…, M Al-Ahmad, F Al-Enezi, S Al-Muhsen… - World allergy …, 2015 - Springer
The prevalence of allergic airway diseases such as asthma and rhinitis has increased
dramatically to epidemic proportions worldwide. Besides air pollution from industry derived …
dramatically to epidemic proportions worldwide. Besides air pollution from industry derived …
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
…, H Al-Saud, F Al-Mulla, F Almourfi, SZ Al-Muhsen… - Science, 2020 - science.org
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
…, J Brooks, M Collins, NM Wolfman, S Al-Muhsen… - Science, 2011 - science.org
Chronic mucocutaneous candidiasis disease (CMCD) is characterized by recurrent or persistent
infections of the skin, nails, and oral and genital mucosae caused by Candida albicans …
infections of the skin, nails, and oral and genital mucosae caused by Candida albicans …
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis
…, A Fischer, S Blanche, S Al-Muhsen… - Journal of Experimental …, 2011 - rupress.org
Chronic mucocutaneous candidiasis disease (CMCD) may be caused by autosomal dominant
(AD) IL-17F deficiency or autosomal recessive (AR) IL-17RA deficiency. Here, using whole…
(AD) IL-17F deficiency or autosomal recessive (AR) IL-17RA deficiency. Here, using whole…
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
…, A Toulon, J Bustamante, S Al-Muhsen… - Journal of Experimental …, 2010 - rupress.org
Most patients with autoimmune polyendocrine syndrome type I (APS-I) display chronic
mucocutaneous candidiasis (CMC). We hypothesized that this CMC might result from …
mucocutaneous candidiasis (CMC). We hypothesized that this CMC might result from …
[HTML][HTML] Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
… Shen-Ying Zhang, Laurent Abel, and Saleh Al-Muhsen contributed equally to this work. …
Shen-Ying Zhang, Laurent Abel, and Saleh Al-Muhsen contributed equally to this work. …
Shen-Ying Zhang, Laurent Abel, and Saleh Al-Muhsen contributed equally to this work. …
[HTML][HTML] IRF8 Mutations and Human Dendritic-Cell Immunodeficiency
…, M Hubeau, J Feinberg, S Al-Muhsen… - … England Journal of …, 2011 - Mass Medical Soc
Background The genetic analysis of human primary immunodeficiencies has defined the
contribution of specific cell populations and molecular pathways in the host defense against …
contribution of specific cell populations and molecular pathways in the host defense against …
Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds
…, L Abel, D Mansouri, R Barbouche, S Al-Muhsen… - Medicine, 2013 - journals.lww.com
Autosomal recessive interleukin (IL)-12 p40 (IL-12p40) deficiency is a rare genetic etiology
of Mendelian susceptibility to mycobacterial disease (MSMD). We report the genetic, …
of Mendelian susceptibility to mycobacterial disease (MSMD). We report the genetic, …
