Diabetes mellitus is increasing at an alarming rate and has become a global challenge. Insulin
resistance in target tissues and a relative deficiency of insulin secretion from pancreatic β-…

Objective: Alterations in plasma concentrations of several trace elements have been reported
to occur in type-1 diabetes mellitus. These micronutrients are suspected to have a role in …

Background Diabetic nephropathy is the single strongest predictor of mortality in patients
with diabetes. The development of overt nephropathy involves important inter-individual …

Rearranged during transfection (RET) is a proto oncogene implicated in thyroid carcinogenesis
of papillary type (PTC). The RET proto-oncogene in PTC is constitutively activated by …

Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder in
pre-menopausal women having complex pathophysiology. Several candidate genes have …

Background Organic cation transporter 1 primarily governs the action of metformin in the liver.
There are considerable inter-individual variations in metformin response. In light of this, it …

Promoter hypermethylation of multiple genes have been identified to play a role in thyroid
cancers and most prominent among them is TSHR gene promoter hypermethylation in …

Background Polycystic ovaries (PCO) and their clinical expression (the polycystic ovary
syndrome [PCOS]) as well as type 2 diabetes mellitus (T2DM) are common medical conditions …

Whereas raised concentrations of lipid peroxides have been found in the plasma and sera
of patients with atherosclerotic coronary artery disease, data about the temporal changes in …

We analysed the pattern of, and predispositions to, infections in patients with diabetes
mellitus admitted in Endocrinology division of a tertiary care hospital. METHODS: The hospital …