A dynamic and mutualistic interaction between tumor cells and tumor microenvironment (
TME ) promotes the progression and metastasis of solid tumors. Cancer immunotherapy is …

Purpose Neratinib is an oral, irreversible pan-ErbB receptor tyrosine kinase inhibitor. The
efficacy and safety of neratinib were evaluated in two cohorts of patients with advanced ErbB2-…

Background Icotinib, an oral EGFR tyrosine kinase inhibitor, had shown antitumour activity
and favourable toxicity in early-phase clinical trials. We aimed to investigate whether icotinib …

Long non-coding RNAs (lncRNAs) are a kind of RNAs with regulation that participate
fundamental cellular processes via diverse mechanisms. Despite the potential importance of …

Intrathoracic lymph node metastases in patients with extrathoracic malignancies are a common
clinical manifestation. Several studies evaluating intrathoracic lymph node metastases in …

MiR-125a has been characterized as a tumor suppressor in several cancers. However, the
role of miR-125a in cervical cancer is unknown. In this study, we found the expression of miR-…

The main aim of this study is to investigate whether baseline lactate dehydrogenase (LDH)
is associated with the clinical outcome of non small‐cell lung cancer (NSCLC) patients …

Background Hepatocellular carcinoma (HCC) is a common cancer associated with a poor
prognosis. Bevacizumab is a monoclonal antibody that binds vascular endothelial growth …

Background: Recent studies have demonstrated the predictive value of pretreatment
neutrophil-to-lymphocyte ratio (NLR) in advanced cancers; however, the role of NLR in patients with …

Background The V325 study showed that docetaxel, cisplatin, and fluorouracil (DCF) prolonged
overall survival (OS) of patients with advanced gastric cancer, but with a high incidence …