Decreased maternal serum adiponectin and increased insulin-like growth factor-1 levels along with increased placental glucose transporter-1 expression in …

…, Z Bobby, G Dorairajan, V Gladwin, V Vinayagam… - Placenta, 2021 - Elsevier
Introduction The placental glucose transporter – 1 (GLUT-1) is involved in the transplacental
glucose transport to the fetus. GLUT-1 expressions are increased in diabetic pregnancies …

[HTML][HTML] Does Vitamin D Supplementation Improve Glycaemic Control In Children With Type 1 Diabetes Mellitus?–A Randomized Controlled Trial

…, M Rajappa, S Kumar, V Vinayagam - Journal of clinical and …, 2017 - ncbi.nlm.nih.gov
Aim To evaluate the role of Vitamin D as an adjuvant in improving glycaemic control and
residual pancreatic beta-cell function. Primary outcome was the mean change in HbA1c levels …

Neuronal biomarkers in predicting neurodevelopmental outcome in term babies with perinatal asphyxia

…, B Adhisivam, SK Bharadwaj, V Vinayagam… - The Indian Journal of …, 2020 - Springer
Objective To assess whether serum levels of neuronal biomarkers (S100 calcium-binding
protein B and Neuron specific enolase) correlate with the neurodevelopmental outcome of …

Gene expression of insulin receptor, insulin-like growth factor increases and insulin-like growth factor-binding protein-3 reduces with increase in prostate size in …

…, LN Dorairajan, M Rajappa, V Vinayagam… - The Aging …, 2018 - Taylor & Francis
Introduction: Although the role of insulin in the development of benign prostatic hyperplasia (BPH)
is well established, there are no studies regarding alteration in the gene expression of …

Placental accumulation of triacylglycerols in gestational diabetes mellitus and its association with altered fetal growth are related to the differential expressions of …

…, SE Jacob, V Gladwin, V Vinayagam… - Experimental and …, 2021 - thieme-connect.com
Introduction Gestational diabetes mellitus (GDM) exhibit altered placental lipid metabolism.
The molecular basis of this altered metabolism is not clear. Altered placental expression of …

Increased placental expressions of nuclear factor erythroid 2–related factor 2 and antioxidant enzymes in gestational diabetes: Protective mechanisms against the …

…, SE Jacob, V Gladwin, V Vinayagam… - European Journal of …, 2019 - Elsevier
Objective: Gestational diabetes mellitus is associated with increased oxidative stress. Oxidative
stress may contribute to the risk for pregnancy pathologies associated with gestational …

Effect of zinc supplementation on relative expression of immune response genes in neonates with sepsis: a preliminary study

N Banupriya, BV Bhat, V Vickneshwaran… - Indian Journal of …, 2020 - journals.lww.com
Methods: In the present study, a sample of convenience of 22 neonates each was selected
from the zinc supplemented and control groups using random numbers for expression of …

[HTML][HTML] Adipokine levels and their association with insulin resistance and fetal outcomes among the newborns of Indian gestational diabetic mothers

…, Z Bobby, G Dorairajan, V Vinayagam… - Saudi medical …, 2019 - ncbi.nlm.nih.gov
Objectives: To investigate the cord blood levels of adipokine and to assess their association
with the fetal insulin resistance and fetal outcomes in newborns of gestational diabetic …

Elevated insulin and reduced insulin like growth factor binding protein-3/prostate specific antigen ratio with increase in prostate size in Benign Prostatic Hyperplasia

…, LN Dorairajan, M Rajappa, V Vinayagam - Clinica Chimica …, 2017 - Elsevier
Background Insulin and insulin like growth factor-1 (IGF-1) have growth promoting effects,
while insulin like growth factor binding protein-3 (IGFBP-3) has growth inhibitory effects. The …

Plasma markers of endothelial dysfunction in patients with hypertensive disorders of pregnancy: a pilot study in a South Indian population

V Vinayagam, Z Bobby, S Habeebullah… - The Journal of …, 2016 - Taylor & Francis
Objectives: To assess the plasma markers of endothelial dysfunction: VonWillebrand factor (vWF),
Platelet derived microparticles (PMPs), and Endothelin-1 (ET-1) in various types of …