Heart failure is associated with the reactivation of a fetal cardiac gene programme that has
become a hallmark of cardiac hypertrophy and maladaptive ventricular remodelling, yet the …

Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization
for heart failure and cardiovascular death among patients with chronic heart failure …

Background Little is know about the outcomes of acute heart failure (AHF) with acute
coronary syndrome (ACS-AHF), compared to those without ACS (NACS-AHF). Methods We …

Diastolic dysfunction is a recognized complication in heart transplant ( HT x) recipients that
limits exercise capacity and is a risk factor for mortality. We investigated the ability of …

Objectives This report describes the baseline clinical profiles and management of DELIVER
(Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction …

BACKGROUND: Pulmonary arterial hypertension (PAH) is a major cause of morbidity and
mortality in patients with systemic sclerosis (SSc). The objective of this study is to describe the …

Aims Obesity is common and associated with unique phenotypic features in heart failure
with preserved ejection fraction (HFpEF). Therefore, understanding the efficacy and safety of …

Aims The aim of this study was to compare the clinical features, predictors, and clinical outcomes
of patients hospitalized with acute heart failure (AHF), with and without worsening heart …

… Waleed Al-Habeeb Waleed Al-Habeeb … Correspondence to Waleed Al-Habeeb, MD,
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, …

Endoplasmic reticulum (ER) stress induction of cell death is implicated in cardiovascular
diseases. Sustained activation of ER-stress induces the unfolded protein response (UPR) …