Doxorubicin- (DOX-) related cardiac injury impairs the life quality of patients with cancer. This
largely limited the clinical use of DOX. It is of great significance to find a novel strategy to …

Since 2015, immunotherapies, especially immune checkpoint inhibitors (ICIs), have made
great breakthroughs in non-small-cell lung cancer (NSCLC). Among them, nivolumab, …

5-Lipoxygenase (5-LOX) has been implicated in the development and progression of lung,
pancreatic and esophageal cancers. However, its role in hepatocellular carcinoma (HCC) …

Objectives: Radiotherapy improves the survival rate of cancer patients, yet it also involves
some inevitable complications. Radiation-induced heart disease (RIHD) is one of the most …

Background. The clinical usefulness of doxorubicin (DOX), an anthracycline with antitumor
activity, is limited by its cardiotoxicity. Oxidative stress and myocardial apoptosis were closely …

Background: Testosterone is critical for maintaining spermatogenesis and male fertility. The
accomplishment of these processes requires the synergistic actions of the classical and non-…

A simple and universal analytical method based on ultra-high performance liquid
chromatography-tandem mass spectrometry (UHPLC-MS/MS) for high throughput screening of 21 …

Background and aims Human mutL homologl ( MLH 1) works coordinately in sequential
steps to initiate repair of DNA mismatches, and aberrant MLH 1 expression is related to …

Aims Currently, available Doppler echocardiographic reference values are derived mainly
from North American and European population studies, which may not applicable to the …

To some extent, the use of metformin may improve endometrial receptivity and pregnancy
outcomes of women with polycystic ovarian syndrome (PCOS) undergoing in vitro fertilization/…