Chemotherapy for advanced gastric cancer
…, M Moehler, W Grothe, WP Yong… - Cochrane database …, 2017 - cochranelibrary.com
Background Gastric cancer is the fifth most common cancer worldwide. In" Western"
countries, most people are either diagnosed at an advanced stage, or develop a relapse after …
countries, most people are either diagnosed at an advanced stage, or develop a relapse after …
Ageing as a risk factor for neurodegenerative disease
Ageing is the primary risk factor for most neurodegenerative diseases, including Alzheimer
disease (AD) and Parkinson disease (PD). One in ten individuals aged ≥65 years has AD …
disease (AD) and Parkinson disease (PD). One in ten individuals aged ≥65 years has AD …
Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label …
…, V Shirinkin, D Sakaeva, N Fadeeva, WP Yong… - The Lancet, 2018 - thelancet.com
Background Patients with advanced gastric or gastro-oesophageal junction cancer that
progresses on chemotherapy have poor outcomes. We compared pembrolizumab with paclitaxel …
progresses on chemotherapy have poor outcomes. We compared pembrolizumab with paclitaxel …
Metal–organic framework-based catalysts with single metal sites
Metal–organic frameworks (MOFs) are a class of distinctive porous crystalline materials
constructed by metal ions/clusters and organic linkers. Owing to their structural diversity, …
constructed by metal ions/clusters and organic linkers. Owing to their structural diversity, …
[HTML][HTML] Safety, efficacy, and pharmacodynamics of tremelimumab plus durvalumab for patients with unresectable hepatocellular carcinoma: randomized expansion of …
PURPOSE This phase I/II study evaluated tremelimumab (anticytotoxic T-lymphocyte–associated
antigen-4 monoclonal antibody) and durvalumab (antiprogrammed death ligand-1 …
antigen-4 monoclonal antibody) and durvalumab (antiprogrammed death ligand-1 …
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic …
Objective Gastric cancer is a major gastrointestinal malignancy for which targeted therapies
are emerging as treatment options. This study sought to identify the most prevalent …
are emerging as treatment options. This study sought to identify the most prevalent …
Infigratinib (BGJ398) in previously treated patients with advanced or metastatic cholangiocarcinoma with FGFR2 fusions or rearrangements: mature results from a …
…, A El-Khoueiry, MJ Borad, WP Yong… - The Lancet …, 2021 - thelancet.com
Background Treatment options are sparse for patients with advanced cholangiocarcinoma
after progression on first-line gemcitabine-based therapy. FGFR2 fusions or rearrangements …
after progression on first-line gemcitabine-based therapy. FGFR2 fusions or rearrangements …
Hypersensitive dual-function luminescence switching of a silver-chalcogenolate cluster-based metal–organic framework
Silver(i) chalcogenide/chalcogenolate clusters are promising photofunctional materials for
sensing, optoelectronics and solar energy harvesting applications. However, their instability …
sensing, optoelectronics and solar energy harvesting applications. However, their instability …
Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a biomarker evaluation from the AVAGAST randomized phase III trial
…, NC Tebbutt, J Ming Xu, W Peng Yong… - Journal of clinical …, 2012 - ascopubs.org
Purpose The AVAGAST study showed that adding bevacizumab to chemotherapy in patients
with advanced gastric cancer improves progression-free survival and tumor response rate …
with advanced gastric cancer improves progression-free survival and tumor response rate …
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
Although the role of miR-200s in regulating E-cadherin expression and epithelial-to-mesenchymal
transition is well established, their influence on metastatic colonization remains …
transition is well established, their influence on metastatic colonization remains …
