User profiles for Abdulrahman E. Koshak

Dr Abdulrahman Koshak

Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King …
Verified email at kau.edu.sa
Cited by 780

[HTML][HTML] Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial

AE Koshak, EA Koshak, AF Mobeireek… - … Therapies in Medicine, 2021 - Elsevier
Abdulrahman Koshak assigned participants to their respective groups. Subsequently, NSO
was delivered to each patient of the treatment group at their isolation place. Compliance was …

[HTML][HTML] Nigella sativa L as a potential phytotherapy for coronavirus disease 2019: A mini review of in silico studies

AE Koshak, EA Koshak - Current Therapeutic Research, 2020 - Elsevier
Background Coronaviruses are responsible for several human diseases, such as the
infectious novel coronavirus disease 2019 (COVID-19), which is caused by severe acute …

[HTML][HTML] Repurposing of some natural product isolates as SARS-COV-2 main protease inhibitors via in vitro cell free and cell-based antiviral assessments and …

…, GA Mohamed, SRM Ibrahim, AE Koshak… - Pharmaceuticals, 2021 - mdpi.com
The emergence of the SARS-CoV-2 pandemic has prompted scientists to search for an efficient
antiviral medicine to overcome the rapid spread and the marked increase in the number …

[HTML][HTML] Comparative Immunomodulatory Activity of Nigella sativa L. Preparations on Proinflammatory Mediators: A Focus on Asthma

AE Koshak, NM Yousif, BL Fiebich… - Frontiers in …, 2018 - frontiersin.org
Introduction: A range of traditional and commercial preparations of NS is frequently used in
the treatment of several inflammatory diseases. Often, these preparations have poor …

Cucurbitacin E glucoside alleviates concanavalin A-induced hepatitis through enhancing SIRT1/Nrf2/HO-1 and inhibiting NF-ĸB/NLRP3 signaling pathways

…, WM Elsaed, A Sirwi, HZ Asfour, AE Koshak… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Cucurbitacins are highly oxygenated tetracyclic
triterpenoids, that represent the major metabolites reported from C. colocynthis (L.) Schrad.. …

Wound Healing Activity of Opuntia ficus-indica Fixed Oil Formulated in a Self-Nanoemulsifying Formulation

AE Koshak, MM Algandaby, MI Mujallid… - International Journal …, 2021 - Taylor & Francis
Introduction Delayed wound healing represents a common health hazard. Traditional herbal
products have been often utilized to promote wound contraction. The current study aimed at …

[HTML][HTML] Metabolic Profiling, Chemical Composition, Antioxidant Capacity, and In Vivo Hepato- and Nephroprotective Effects of Sonchus cornutus in Mice Exposed to …

…, ET Mehanna, AS Wahba, MA Elfaky, AE Koshak… - Antioxidants, 2022 - mdpi.com
Sonchus cornutus (Asteraceae) is a wild. edible plant that represents a plentiful source of
polyphenolic compounds. For the first time, the metabolic analysis profiling demonstrated the …

[HTML][HTML] Meleagrin Isolated from the Red Sea Fungus Penicillium chrysogenum Protects against Bleomycin-Induced Pulmonary Fibrosis in Mice

…, MS Goda, ET Mehanna, MA Elfaky, AE Koshak… - Biomedicines, 2022 - mdpi.com
The Red Sea marine fungus Penicillium chrysogenum (Family: Ascomycota) comprises a
panel of chemically diverse natural metabolites. A meleagrin alkaloid was isolated from deep-…

[HTML][HTML] Terretonin as a new protective agent against sepsis-induced acute lung injury: Impact on SIRT1/Nrf2/NF-κBp65/NLRP3 signaling

…, WM Elsaed, A Sirwi, HZ Asfour, AE Koshak… - Biology, 2021 - mdpi.com
Simple Summary Acute lung injury (ALI) is a severe inflammatory pulmonary disorder that
still causes a high mortality rate. As the current therapeutic strategies have not been effective …

[HTML][HTML] Phenolics from Chrozophora oblongifolia Aerial Parts as Inhibitors of α-Glucosidases and Advanced Glycation End Products: In-Vitro Assessment, Molecular …

…, GA Mohamed, AB Abdel-Naim, AE Koshak… - Biology, 2022 - mdpi.com
Simple Summary The chemical investigation of Chrozophora oblongifolia aerial parts resulted
in the isolation of five phenolic compounds. The isolated metabolites were tested for their …