Nocardiosis is a cause of significant morbidity and mortality in the immunocompromised host,
and is an infrequent complication of tumor necrosis factor alpha (TNF-α) blockers in …

The presents a case study of two patients who have sickle cell disease (SCD) and who
were treated with sirolimus as part of their post-kidney transplantation immunosuppressive …

Case Report. The patient was a 25-year-old Saudi Arabian woman suffering from SCD with
frequent vaso-occlusive crises. She had more than 6 episodes per year requiring hospital …

Listeria monocytogenes is an uncommon cause of illness in the general population.
Meningoencephalitis is the most common central nervous system (CNS) manifestation of listeriosis. …

Stimulating the production of fetal hemoglobin may benefit patients with sickle cell anemia
by inhibiting sickling. We gave pulsed treatments with high doses of recombinant human …

Sickle cell nephropathy is a severe complication of sickle cell disease (SCD) that has a wide
range of manifestations, from asymptomatic microalbuminuria to end-stage renal disease (…

Physiologic principles underlying the differences in fetal hemoglobin (HbF) induction between
acute and chronic states of erythroid expansion are poorly understood. Whereas abrupt …

During the last several years, studies in humans and experimental animals have identified
several compounds that induce fetal hemoglobin in the adult. These include: cell-cycle-…

Background. Proteinuria is a common feature of sickle cell nephropathy (SCN) that can progress
to renal insufficiency and end stage renal disease. Microalbuminuria (MA) is the earliest …

Proteinuria is a complication of sickle cell nephropathy that can progress to renal insufficiency
and end-stage renal disease. The magnitude of proteinuria among patients with sickle cell …