User profiles for Assim Alfadda

Assim Alfadda

King Saud University
Verified email at ksu.edu.sa
Cited by 4239

[HTML][HTML] Reactive oxygen species in health and disease

AA Alfadda, RM Sallam - BioMed research international, 2012 - hindawi.com
During the past decades, it became obvious that reactive oxygen species (ROS) exert a
multitude of biological effects covering a wide spectrum that ranges from physiological …

Renin-angiotensin system at the interface of COVID-19 infection

R Gul, UH Kim, AA Alfadda - European Journal of Pharmacology, 2021 - Elsevier
Angiotensin-converting enzyme 2 (ACE2) has been recognized as a potential entry receptor
for SARS-CoV-2 infection. Binding of SARS-CoV-2 to ACE2 allows engagement with …

Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance

…, AF Bassas, RM Sallam, KS Park, AA Alfadda… - Nature …, 2015 - nature.com
Adiponectin plays a key role in the regulation of the whole-body energy homeostasis by
modulating glucose and lipid metabolism. Although obesity-induced reduction of adiponectin …

[HTML][HTML] Mapping COVID-19 related research from Saudi Arabia, a scoping review: between reality and dreams

…, T Islam, N Alamro, A Alsultan, A Alfadda… - Saudi medical …, 2020 - ncbi.nlm.nih.gov
Objectives: To map research production by Saudi-affiliated investigators in order to identify
areas of strength and weakness. Method: We followed the Arksey and O’Malley (2005) …

Gaps to bridge: misalignment between perception, reality and actions in obesity

ID Caterson, AA Alfadda, P Auerbach… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aims Despite increased recognition as a chronic disease, obesity remains greatly
underdiagnosed and undertreated. We aimed to identify international perceptions, attitudes, …

Hyaluronic acid coated chitosan nanoparticles reduced the immunogenicity of the formed protein corona

…, IO Alanazi, I Alradwan, MA Majrashi, AA Alfadda… - Scientific reports, 2017 - nature.com
Studying the interactions of nanoparticles (NPs) with serum proteins is necessary for the
rational development of nanocarriers. Optimum surface chemistry is a key consideration to …

[HTML][HTML] Subacute thyroiditis: clinical presentation and long term outcome

AA Alfadda, RM Sallam, GE Elawad… - International journal of …, 2014 - hindawi.com
Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the
clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to …

Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation

…, HJ Son, H Masuzaki, K Hotta, AA Alfadda… - Journal of Biological …, 2010 - ASBMB
Orosomucoid (ORM), also called α-1 acid glycoprotein, is an abundant plasma protein that
is an immunomodulator induced by stressful conditions such as infections. In this study, we …

A novel function of adipocytes in lipid antigen presentation to iNKT cells

…, YS Lee, JH Sohn, SK Lee, AA Alfadda… - … and cellular biology, 2013 - Taylor & Francis
Systemic low-grade chronic inflammation has been intensively investigated in obese subjects.
Recently, various immune cell types, such as macrophages, granulocytes, helper T cells, …

[HTML][HTML] Differential patterns of serum concentration and adipose tissue expression of chemerin in obesity: adipose depot specificity and gender dimorphism

AA Alfadda, RM Sallam, MA Chishti, AS Moustafa… - Molecules and cells, 2012 - Elsevier
Chemerin, a recognized chemoattractant, is expressed in adipose tissue and plays a role in
adipocytes differentiation and metabolism. Gender- and adipose tissue-specific differences …