User profiles for Bahjat Al-Ani
 | Bahjat Al-AniPhysiology Department, College of Medicine, King Khalid University Verified email at kku.edu.sa Cited by 4551 |
Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1
Background— Preeclampsia is characterized clinically by hypertension and proteinuria.
Soluble Flt-1 (sFlt-1; also known as soluble vascular endothelial growth factor receptor-1 […
Soluble Flt-1 (sFlt-1; also known as soluble vascular endothelial growth factor receptor-1 […
[HTML][HTML] Anti-proteinase 3 anti-neutrophil cytoplasm autoantibodies recapitulate systemic vasculitis in mice with a humanized immune system
Evidence is lacking for direct pathogenicity of human anti-proteinase-3 (PR3) antibodies in
development of systemic vasculitis and granulomatosis with polyangiitis (GPA, Wegener's …
development of systemic vasculitis and granulomatosis with polyangiitis (GPA, Wegener's …
Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1 …
A Kawabata, M Saifeddine, B Al-Ani, L Leblond… - … of Pharmacology and …, 1999 - ASPET
We developed a calcium signaling-based assay, using cultured human embryonic kidney
cells (HEK), that evaluates simultaneously, the activation/desensitization or blockade of the …
cells (HEK), that evaluates simultaneously, the activation/desensitization or blockade of the …
Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides
MD Hollenberg, M Saifeddine, B Al-Ani… - Canadian journal of …, 1997 - cdnsciencepub.com
We have used three distinct bioassay systems (rat aorta (RA) relaxation; rat gastric longitudinal
muscle (LM) contraction; human embryonic kidney 293 (HEK293) cell calcium signal) to …
muscle (LM) contraction; human embryonic kidney 293 (HEK293) cell calcium signal) to …
[HTML][HTML] The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis
VEGF-A activity is tightly regulated by ligand and receptor availability. Here we investigate
the physiological function of heterodimers between VEGF receptor-1 (VEGFR-1; Flt-1) and …
the physiological function of heterodimers between VEGF receptor-1 (VEGFR-1; Flt-1) and …
Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide–mediated angiogenesis
Vascular endothelial growth factor-A (VEGF) is critical for angiogenesis but fails to induce
neovascularization in ischemic tissue lesions in mice lacking endothelial nitric oxide synthase (…
neovascularization in ischemic tissue lesions in mice lacking endothelial nitric oxide synthase (…
Thrombin and mast cell tryptase regulate guinea‐pig myenteric neurons through proteinase‐activated receptors‐1 and− 2
…, P Gamp, M Thoma, B Al‐Ani… - The Journal of …, 1999 - Wiley Online Library
1 Proteases regulate cells by cleaving proteinase‐activated receptors (PARs). Thrombin
and trypsin cleave PAR‐1 and PAR‐2 on neurons and astrocytes of the brain to regulate …
and trypsin cleave PAR‐1 and PAR‐2 on neurons and astrocytes of the brain to regulate …
Rat proteinase‐activated receptor‐2 (PAR‐2): cDNA sequence and activity of receptor‐derived peptides in gastric and vascular tissue
M Saifeddine, B Al‐Ani, CH Cheng… - British journal of …, 1996 - Wiley Online Library
1 The biological activities of the proteinase‐activated receptor number 2 (PAR‐2)‐derived
peptides, SLIGRL (PP6) SLIGRL‐NH 2 (PP6‐NH 2 ) and SLIGR‐NH 2 (PP5‐NH 2 ) were …
peptides, SLIGRL (PP6) SLIGRL‐NH 2 (PP6‐NH 2 ) and SLIGR‐NH 2 (PP5‐NH 2 ) were …
Resveratrol inhibits the release of soluble fms-like tyrosine kinase (sFlt-1) from human placenta
OBJECTIVE: Soluble vascular endothelial growth factor receptor–1 (also know as soluble
fms-like tyrosine kinase [sFlt]-1) is a key causative factor of preeclampsia. Resveratrol, a plant …
fms-like tyrosine kinase [sFlt]-1) is a key causative factor of preeclampsia. Resveratrol, a plant …
Metformin inhibits mTOR–HIF‐1α axis and profibrogenic and inflammatory biomarkers in thioacetamide‐induced hepatic tissue alterations
… Haidara and Bahjat Al-Ani equally contributed to this work. … Haidara and Bahjat Al-Ani
equally contributed to this work. … Haidara and Bahjat Al-Ani equally contributed to this work. …
equally contributed to this work. … Haidara and Bahjat Al-Ani equally contributed to this work. …