European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years

…, G Piacentini, D Rigau, B Rottier… - European respiratory …, 2021 - Eur Respiratory Soc
Background Diagnosing asthma in children represents an important clinical challenge. There
is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-…

Monitoring asthma in children

…, G Piacentini, D Price, BL Rottier… - European …, 2015 - Eur Respiratory Soc
The goal of asthma treatment is to obtain clinical control and reduce future risks to the
patient. To reach this goal in children with asthma, ongoing monitoring is essential. While all …

The pharmacokinetics of antibiotics in cystic fibrosis

…, P Hagedoorn, HW Frijlink, BL Rottier… - Expert opinion on …, 2021 - Taylor & Francis
Introduction Dosing of antibiotics in people with cystic fibrosis (CF) is challenging, due to
altered pharmacokinetics, difficulty of lung tissue penetration, and increasing presence of …

Changes in Performance of the Pari eFlow® Rapid and Pari LC Plus™ during 6 Months Use by CF Patients

BL Rottier, CJP van Erp, TS Sluyter… - Journal of aerosol …, 2009 - liebertpub.com
Background: Nebulized antibiotics are important in the treatment of cystic fibrosis. The Pari
eFlow ® rapid with vibrating mesh is often used off-label for the administration of tobramycin (…

A virtual asthma clinic for children: fewer routine outpatient visits, same asthma control

…, ERVM Rikkers-Mutsaerts, BL Rottier… - European …, 2017 - Eur Respiratory Soc
eHealth is an appealing medium to improve healthcare and its value (in addition to standard
care) has been assessed in previous studies. We aimed to assess whether an eHealth …

Online asthma management for children is cost-effective

…, ERVM Rikkers-Mutsaerts, BL Rottier… - European …, 2017 - Eur Respiratory Soc
eHealth interventions have been proposed as an appealing method to improve health
outcomes and reduce healthcare costs [1–3]. However, the development of an eHealth …

[HTML][HTML] Effect of inhaler design variables on paediatric use of dry powder inhalers

AJ Lexmond, TJ Kruizinga, P Hagedoorn, BL Rottier… - PLoS …, 2014 - journals.plos.org
Age appropriateness is a major concern of pulmonary delivery devices, in particular of dry
powder inhalers (DPIs), since their performance strongly depends on the inspiratory flow …

Ciclesonide versus other inhaled corticosteroids for chronic asthma in children

S Kramer, BL Rottier, RJPM Scholten… - Cochrane Database …, 1996 - cochranelibrary.com
Background Inhaled corticosteroids (ICS) are the cornerstone of asthma maintenance
treatment in children. Particularly among parents, there is concern about the safety of ICS as …

Asthma medication delivery: mists and myths

BL Rottier, BK Rubin - Paediatric respiratory reviews, 2013 - Elsevier
Asthma is usually treated with inhaled corticosteroids (ICS) and bronchodilators generated
from pressurized metered dose inhalers (pMDI), dry powder inhalers (DPI), or nebulizers. The …

Monitoring asthma in childhood: management-related issues

BL Rottier, E Eber, G Hedlin, S Turner… - European …, 2015 - Eur Respiratory Soc
Management-related issues are an important aspect of monitoring asthma in children in
clinical practice. This review summarises the literature on practical aspects of monitoring …