[HTML][HTML] Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2
L Wei, K Li, X Pang, B Guo, M Su, Y Huang… - Journal of Experimental …, 2016 - Springer
Background Accumulating researches have shown that epithelial-mesenchymal transition (EMT)
contributes to tumor metastasis. Leptin, a key adipokine secreted from adipocytes, …
contributes to tumor metastasis. Leptin, a key adipokine secreted from adipocytes, …
A simple and smart AND-gate DNA nanoprobe for correlated enzymes tracking and cell-selective imaging
Z Zeng, B Guo, X Li, X Fu, Y Chen, H Wu… - Biosensors and …, 2022 - Elsevier
Accurate cancer diagnosis and effective drug therapy entail sensitive and dynamic monitoring
of intracellular key enzymes, since their expression level is closely related to disease …
of intracellular key enzymes, since their expression level is closely related to disease …
[HTML][HTML] PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α
…, H Chen, Q Zeng, F Jin, Y Ye, Z Ou, M Guo, B Guo… - Genes & …, 2024 - Elsevier
Pyruvate dehydrogenase kinase 1 (PDK1) phosphorylates the pyruvate dehydrogenase
complex, which inhibits its activity. Inhibiting pyruvate dehydrogenase complex inhibits the …
complex, which inhibits its activity. Inhibiting pyruvate dehydrogenase complex inhibits the …
Silencing of the annexin II gene down-regulates the levels of S100A10, c-Myc, and plasmin and inhibits breast cancer cell proliferation and invasion.
J Zhang, B Guo, Y Zhang, J Cao, T Chen - Saudi medical journal, 2010 - europepmc.org
Objective To explore the roles of annexin II in breast cancer progression, and to study the
effect of annexin II on breast cancer cell proliferation and invasion. Methods This study was …
effect of annexin II on breast cancer cell proliferation and invasion. Methods This study was …
Performance of simultaneous carbon and nitrogen removal of high-salinity wastewater in heterotrophic nitrification-aerobic denitrification mode
K Song, Y Gao, Y Yang, BQ Guo, YZ Wang - Journal of Environmental …, 2023 - Elsevier
In this work, heterotrophic nitrification-aerobic denitrification (HN-AD) mode was successfully
established after a 105-day acclimation in a sequencing batch reactor (SBR) system using …
established after a 105-day acclimation in a sequencing batch reactor (SBR) system using …
PDK1‐stabilized LncRNA SPRY4‐IT1 promotes breast cancer progression via activating NF‐κB signaling pathway
…, R Zhang, T Chen, C Chai, B Guo - Molecular …, 2023 - Wiley Online Library
Pyruvate dehydrogenase kinase 1 (PDK1) is a widely known glycolytic enzyme, and some
evidence showed that PDK1 promoted breast cancer by multiple approaches. However, very …
evidence showed that PDK1 promoted breast cancer by multiple approaches. However, very …
Clinical significance of the serum IgM and IgG to SARS‐CoV‐2 in coronavirus disease‐2019
…, D Gou, G Fu, J Wang, B Guo - Journal of Clinical …, 2021 - Wiley Online Library
Objective To explore the clinical value of serum IgM and IgG to SARS‐CoV‐2 in COVID‐19.
Methods 105 COVID‐19 patients were enrolled as the disease group. 197 non‐COVID‐19 …
Methods 105 COVID‐19 patients were enrolled as the disease group. 197 non‐COVID‐19 …
[HTML][HTML] Downregulation of PHLPP induced by endoplasmic reticulum stress promotes eIF2α phosphorylation and chemoresistance in colon cancer
Aberrant activation of endoplasmic reticulum (ER) stress by extrinsic and intrinsic factors
contributes to tumorigenesis and resistance to chemotherapies in various cancer types. Our …
contributes to tumorigenesis and resistance to chemotherapies in various cancer types. Our …
Postconditioning with sevoflurane or propofol alleviates lipopolysaccharide-induced neuroinflammation but exerts dissimilar effects on the NR2B subunit and …
H Liu, B Chen, B Guo, X Deng, B Wang, X Dou - Molecular Neurobiology, 2021 - Springer
Neuroinflammation can cause cognitive deficits, and preexisting neuroinflammation is
observed frequently in the clinic after trauma, surgery, and infection. Patients with preexisting …
observed frequently in the clinic after trauma, surgery, and infection. Patients with preexisting …
[HTML][HTML] Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis
Intervertebral disc (IVD) degeneration is the leading cause of disability with no disease-modifying
treatment. IVD degeneration is associated with instable mechanical loading in the …
treatment. IVD degeneration is associated with instable mechanical loading in the …