User profiles for Bikash Medhi

PROF. BIKASH MEDHI

Department of Pharmacology, PGIMER
Verified email at pgimer.edu.in
Cited by 8302

In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)

…, H Kumar, A Prakash, DP Dhibar, B Medhi - Journal of …, 2021 - Taylor & Francis
The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV)
binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex, …

Serum ferritin as a predictive biomarker in COVID-19. A systematic review, meta-analysis and meta-regression analysis

…, PK Panda, S Vivekanandan, BJ Omar, B Medhi… - Journal of critical …, 2022 - Elsevier
Ferritin is a known inflammatory biomarker in COVID-19. However, many factors and co-morbidities
can confound the level of serum ferritin. This current metaanalysis evaluates serum …

Galantamine-loaded solid–lipid nanoparticles for enhanced brain delivery: preparation, characterization, in vitro and in vivo evaluations

S Misra, K Chopra, VR Sinha, B Medhi - Drug delivery, 2016 - Taylor & Francis
Galantamine hydrobromide, a promising acetylcholinesterase inhibitor is reported to be
associated with cholinergic side effects. Its poor brain penetration results in lower bioavailability …

Pharmacokinetic and toxicological profile of artemisinin compounds: an update

B Medhi, S Patyar, RS Rao, P Byrav DS, A Prakash - Pharmacology, 2009 - karger.com
Artemisinin has been used effectively in malaria treatment. With the emerging resistance to
malaria, the optimum and judicial use of the drug has become important. The drug …

Drug targets for corona virus: A systematic review

…, H Kumar, S Bansal, B Medhi - Indian journal of …, 2020 - journals.lww.com
The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21 th century. However,
the lack of specific drugs to prevent/treat an attack is a major need at this current point of …

Role of vinpocetine in cerebrovascular diseases

S Patyar, A Prakash, M Modi, B Medhi - Pharmacological Reports, 2011 - Springer
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit,
which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow …

Virological and clinical cure in COVID‐19 patients treated with hydroxychloroquine: a systematic review and meta‐analysis

…, DP Dhibar, A Prakash, B Medhi - Journal of medical …, 2020 - Wiley Online Library
Following the demonstration of the efficacy of hydroxychloroquine against severe acute
respiratory syndrome coronavirus 2 in vitro, many trials started to evaluate its efficacy in clinical …

Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics

S Thakur, R Dhapola, P Sarma, B Medhi, DHK Reddy - Inflammation, 2023 - Springer
Alzheimer’s disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …

Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes

…, S Sharma, P Sarma, A Prakash, B Medhi - Pharmacological …, 2021 - Springer
Introduction COVID-19 cases are on surge; however, there is no efficient treatment or vaccine
that can be used for its management. Numerous clinical trials are being reviewed for use …

[HTML][HTML] Challenges of drug-resistant malaria

S Sinha, B Medhi, R Sehgal - Parasite, 2014 - ncbi.nlm.nih.gov
Over the past six decades, the drug resistance of Plasmodium falciparum has become an
issue of utmost concern. Despite the remarkable progress that has been made in recent years …