Functional venomics of the Sri Lankan Russell's viper (Daboia russelii) and its toxinological correlations

…, SY Fung, KY Tan, MKK Yap, CA Gnanathasan… - Journal of …, 2015 - Elsevier
The venom proteome (venomics) of the Sri Lankan Daboia russelii was elucidated using 1D
SDS PAGE nano-ESI-LCMS/MS shotgun proteomics. A total of 41 different venom proteins …

[HTML][HTML] Clinical management of snakebite envenoming: future perspectives

M Hamza, C Knudsen, CA Gnanathasan, W Monteiro… - Toxicon: X, 2021 - Elsevier
Snakebite envenoming is a major cause of morbidity and mortality in rural communities
throughout the tropics. Generally, the main clinical features of snakebites are local swelling, …

[HTML][HTML] Venom concentrations and clotting factor levels in a prospective cohort of Russell's viper bites with coagulopathy

…, MA O'Leary, CA Gnanathasan… - PLoS neglected …, 2015 - journals.plos.org
Background Russell’s viper envenoming is a major problem in South Asia and causes
venom induced consumption coagulopathy. This study aimed to investigate the kinetics and …

[HTML][HTML] Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell's viper (Daboia russelii) venoms

…, KY Tan, NH Tan, SM Sim, CA Gnanathasan… - Journal of Venomous …, 2021 - SciELO Brasil
Background: The western Russell’s viper (Daboia russelii) is widely distributed in South Asia,
and geographical venom variation is anticipated among distant populations. Antivenoms …

Hump-nosed pit viper (Hypnale hypnale) envenoming causes mild coagulopathy with incomplete clotting factor consumption

…, H Karunathilake, LF Lincz, CA Gnanathasan… - Clinical …, 2013 - Taylor & Francis
Context. Limited information exists on the coagulopathy caused by hump-nosed pit viper (Hypnale
hypnale) envenoming. Objectives. This study aimed to characterise the coagulopathy …

Proteomic investigation of Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom

CH Tan, NH Tan, SM Sim, SY Fung, CA Gnanathasan - Toxicon, 2015 - Elsevier
The hump-nosed pit viper, Hypanle hypnale, contributes to snakebite mortality and morbidity
in Sri Lanka. Studies showed that the venom is hemotoxic and nephrotoxic, with some …

[HTML][HTML] Acute renal failure following oxalic acid poisoning: a case report

U Dassanayake, CA Gnanathasan - Journal of occupational medicine and …, 2012 - Springer
Oxalic acid poisoning is being recognized as an emerging epidemic in the rural communities
of Sri Lanka as it is a component of locally produced household laundry detergents. Herein …

[HTML][HTML] Acute ischemic stroke following Hump-nosed viper envenoming; first authenticated case

V Jeevagan, T Chang, CA Gnanathasan - Thrombosis journal, 2012 - Springer
Hump-nosed pit viper (Genus Hypnale) is a medically important venomous snake in Sri Lanka
and Southwestern India which causes significant morbidity and mortality. Envenoming of …

[HTML][HTML] Elucidating the Venom Diversity in Sri Lankan Spectacled Cobra (Naja naja) through De Novo Venom Gland Transcriptomics, Venom Proteomics and …

KY Wong, KY Tan, NH Tan, CA Gnanathasan, CH Tan - Toxins, 2021 - mdpi.com
Inadequate effectiveness of Indian antivenoms in treating envenomation caused by the
Spectacled Cobra/Indian Cobra (Naja naja) in Sri Lanka has been attributed to geographical …

Acute pituitary insufficiency and hypokalaemia following envenoming by Russell's viper (Daboia russelii) in Sri Lanka: Exploring the pathophysiological mechanisms

V Jeevagan, P Katulanda, CA Gnanathasan… - Toxicon, 2013 - Elsevier
Russell's viper envenoming is associated with a high incidence of morbidity and mortality.
Hypopituitarism following envenoming by Russell's vipers is a well recognized sequel in …