[HTML][HTML] Animal models of glaucoma

…, J Dunmire, A Sewell, DP Edward - BioMed Research …, 2012 - hindawi.com
Glaucoma is a heterogeneous group of disorders that progressively lead to blindness due
to loss of retinal ganglion cells and damage to the optic nerve. It is a leading cause of …

A review of the efficacy of mitomycin C in glaucoma filtration surgery

…, LA Aljasim, O Owaidhah, DP Edward - Clinical …, 2015 - Taylor & Francis
The success of trabeculectomy, which is considered the gold standard in the surgical
treatment of glaucoma, depends on the wound healing response. The introduction of …

Newer advances in medical management of glaucoma

…, N Nazm, R Mehta, DP Edward - Indian journal of …, 2022 - journals.lww.com
The burden of irreversible vision loss from Glaucoma continues to rise. While the disease
pathogenesis is not well understood, intraocular pressure (IOP) is the only modifiable risk …

Matrix metalloproteinases and tumor necrosis factor α in glaucomatous optic nerve head

…, G Tezel, MB Wax, DP Edward - Archives of ophthalmology, 2000 - jamanetwork.com
Objective To study expression and location of matrix metalloproteinases (MMPs) and tumor
necrosis factor α (TNF-α) in glaucomatous optic nerve heads, which are known to be …

Serum autoantibodies to optic nerve head glycosaminoglycans in patients with glaucoma

G Tezel, DP Edward, MB Wax - Archives of ophthalmology, 1999 - jamanetwork.com
Background Serum autoantibodies that cross-react with glycosaminoglycans have been
proposed to play a significant role in specific tissue injury in patients with systemic autoimmune …

Visual acuity and intraocular pressure after Descemet's stripping endothelial keratoplasty in eyes with and without preexisting glaucoma

…, MO Price, FW Price, W Gao, JT Wilensky, DP Edward - Ophthalmology, 2009 - Elsevier
PURPOSE: (1) To characterize the pattern of intraocular pressure (IOP) changes after
Descemet's stripping endothelial keratoplasty (DSEK) in patients without preexisting glaucoma …

Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retina.

KU Löffler, DP Edward, MO Tso - … ophthalmology & visual …, 1995 - iovs.arvojournals.org
PURPOSE: Increased immunoreactivity (IR) of beta-amyloid and the amyloid-associated
proteins tau and amyloid precursor protein (APP) in the brain have been linked to the …

Apoptotic photoreceptor cell death after traumatic retinal detachment in humans

CJ Chang, WW Lai, DP Edward… - Archives of …, 1995 - jamanetwork.com
Objective: To determine the mechanism of photoreceptor cell death after traumatic retinal
detachment in humans. Design: Clinical records from 1975 to 1993 of 75 patients, whose eyes …

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

…, N Kobakhidze, R George, L Vijaya, T Do, DP Edward… - Nature …, 2017 - nature.com
Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma
and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, …

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

…, JH Fingert, M Inatani, K Tashiro, A Reis, DP Edward - Nature …, 2015 - nature.com
Exfoliation syndrome (XFS) is the most common recognizable cause of open-angle
glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome-wide …