Potential of the Polymerase Chain Reaction in the Diagnosis of Active Toxoplasma Infection by Detection of Parasite in Blood

EC Guy, DHM Joynson - Journal of Infectious Diseases, 1995 - academic.oup.com
Blood samples from 54 patients presenting with acute toxoplasmic lymphadenopathy were
tested for the presence of Toxoplasma gondii DNA using a nested polymerase chain reaction …

Molecular evidence for multiple Toxoplasma gondii infections in individual patients in England and Wales: public health implications

TV Aspinall, EC Guy, KE Roberts, DHM Joynson… - International journal for …, 2003 - Elsevier
We sought to determine the SAG2 genotypes of Toxoplasmagondii associated with cases of
acute human toxoplasmosis in England and Wales. The samples examined were collected …

Clinical and metabolic effects associated with weight changes and obeticholic acid in non‐alcoholic steatohepatitis

…, S Buie, A Mae Diehl, C Guy, C Kigongo… - Alimentary …, 2018 - Wiley Online Library
Background In a 72‐week, randomised controlled trial of obeticholic acid ( OCA ) in non‐alcoholic
steatohepatitis ( NASH ), OCA was superior to placebo in improving serum ALT levels …

Borrelia burgdorferi in urban parks.

EC Guy, RG Farquhar - 1991 - cabidigitallibrary.org
Following serological confirmation of infection with B. burgdorferi in a sick dog at Richmond
in south-west London, UK, in 1988, ticks were collected from 2 parks and tested by …

Evaluation of a Candidate International Standard Preparation for Human Anti-Toxoplasma Immunoglobulin G

P Rigsby, S Rijpkema, EC Guy, J Francis… - Journal of clinical …, 2004 - Am Soc Microbiol
A freeze-dried human serum preparation containing immunoglobulin G (IgG) to Toxoplasma
gondii was assessed for its suitability as an international reference reagent in an …

The prevalence of cryptosporidiosis in Turkish children, and genotyping of isolates by nested polymerase chain reaction-restriction fragment length polymorphism.

GS Tamer, M Turk, H Dagci, B Pektas, EC Guy… - Saudi medical …, 2007 - europepmc.org
Methods This study was conducted in the Department of Parasitology, Faculty of Medicine,
Ege University, Turkey during a 3-month period in 2006. We assessed the fecal samples of …

[HTML][HTML] Isolation and characterization of Borrelia burgdorferi strains from Ixodes ricinus ticks in the southern England

…, A Ramazani, A Karami, R Ranjbar, EC Guy - BioImpacts …, 2015 - ncbi.nlm.nih.gov
… After subculture, isolates were suspended in BSK-II medium containing 40% (v/v) glycerol
and then stored at -135 C. The sources of the laboratory strains of Borrelia used in this study …

Use of the polymerase chain reaction in the diagnosis of acquired ocular toxoplasmosis in an immunocompetent adult.

RM Manners, S O'Connell, EC Guy… - The British Journal of …, 1994 - ncbi.nlm.nih.gov
… Ruth M Manners, Susan O'Connell, Edward C Guy, David HM Joynson, Christopher R
Canning, David E Etchells … PHLS, Toxoplasma Reference Laboratory, Singleton Hospital …

Planarity and constraint of the carbonyl groups in 1, 2-diones are determinants for selective inhibition of human carboxylesterase 1

…, LD Hicks, MJ Hatfield, CC Edwards… - Journal of medicinal …, 2007 - ACS Publications
Carboxylesterases (CE) are ubiquitous enzymes responsible for the detoxification of
xenobiotics, including numerous clinically used drugs. Therefore, the selective inhibition of these …

[HTML][HTML] Establishment of replacement International Standard 13/132 for human antibodies to Toxoplasma gondii

S Rijpkema, J Hockley, P Rigsby, EC Guy… - Biologicals, 2016 - Elsevier
Sixteen laboratories carried out a collaborative study to validate 13/132 as a replacement
International Standard (IS) for TOXM (3rd IS for anti-Toxoplasma Serum, Human, 1000 IU). 13/…