Recent evidence suggests that neural stem/precursor cells (NPCs) promote recovery in
animal models with delayed neuronal death via a number of indirect bystander effects. A …

Based on its trophic influence on neurons and vascular cells, vascular endothelial growth
factor (VEGF) is a promising candidate for stroke treatment. VEGF’s survival-promoting effects …

Therapeutic angiogenesis with vascular endothelial growth factor (VEGF) is a clinically
promising strategy in ischaemic disease. The pathophysiological consequences of enhanced …

Apart from its hematopoietic function, erythropoietin (Epo) exerts neuroprotective functions in
brain hypoxia and ischemia. To examine the mechanisms mediating Epo's neuroprotective …

This article summarizes the evidence that endogenously produced and exogenously
administered melatonin reduces the degree of tissue damage and limits the biobehavioral deficits …

Based on its trophic effects on neurons and vascular cells, vascular endothelial growth
factor (VEGF) is a promising candidate for the treatment of neurodegenerative diseases. To …

Background Cisplatin, one of the most effective and potent anticancer drugs, is used in the
treatment of a wide variety of both pediatric and adult malignancies. However, the …

Large infarcts develop in pinealectomized rats subjected to middle cerebral artery occlusion,
which was attributed to loss of antioxidant action of melatonin. However, melatonin also has …

Background and Purpose— Delivery of therapeutic proteins into tissues and across the
blood-brain barrier is severely limited by their size and biochemical properties. The 11-amino …

The promotion of post-ischaemic motor recovery remains a major challenge in clinical
neurology. Recently, plasticity-promoting effects have been described for the growth factor …