Tumor heterogeneity predicts metastatic potential in colorectal cancer

…, BY Oh, HK Hong, H Al-Khalidi, F Al-Alem… - Clinical Cancer …, 2017 - AACR
Purpose: Tumors continuously evolve to maintain growth; secondary mutations facilitate this
process, resulting in high tumor heterogeneity. In this study, we compared mutations in …

[HTML][HTML] Preoperative selection of patients with colorectal cancer liver metastasis for hepatic resection

RE Mattar, F Al-Alem, E Simoneau… - World journal of …, 2016 - ncbi.nlm.nih.gov
Surgical resection of colorectal liver metastases (CRLM) has a well-documented improvement
in survival. To benefit from this intervention, proper selection of patients who would be …

Morbidity, mortality and predictors of outcome following hepatectomy at a Saudi tertiary care center

F Al-Alem, RE Mattar, OA Fadl, A Alsharabi… - Annals of Saudi …, 2016 - annsaudimed.net
BACKGROUND : Hepatic resection is a major surgical procedure. Data on outcomes of
hepatectomy in Saudi Arabia are scarce. OBJECTIVE : To measure morbidity and mortality and …

[HTML][HTML] Colorectal cancer liver metastasis trends in the kingdom of Saudi Arabia

M Hassanain, F Al-Alem, E Simoneau… - Saudi Journal of …, 2016 - journals.lww.com
Results: 427 cases of CRC with a mean age at diagnosis of 55.47±12.85 years, out of which
96% were resected. Stage II was predominant at presentation, followed by both stage III and …

[HTML][HTML] Comparison study between open and laparoscopic liver resection in a Saudi tertiary center

FA Al-Saif, MK Aldekhayel, F Al-Alem… - Saudi Medical …, 2019 - ncbi.nlm.nih.gov
Objectives: To compare King Saud University Medical City experience in laparoscopic liver
resection with our previously established database for open resections. Methods: A …

[HTML][HTML] Pancreatic tuberculosis in immunocompetent patients: At the University Hospital in Kingdom of Saudi Arabia

…, AM Aljebreen, AB Alsharaabi, FA Alalem… - Saudi Medical …, 2019 - ncbi.nlm.nih.gov
Objectives: To raise awareness of practitioners on benign treatable conditions such as
pancreatic tuberculosis (TB). Methods: A retrospective study at King Khaled University Hospital, …

[HTML][HTML] The overall survival rate for patients with hepatocellular carcinoma who underwent hepatic resection or radiofrequency ablation procedure for curative intent

…, EA Robles, F Al-Saif, F Al-Alem… - Journal of Nature and …, 2019 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) is currently one of the leading causes of
cancer-related deaths worldwide. According to the data obtained from the last Saudi Cancer …

Incidental gallbladder cancer

F Al-alem, RE Mattar, A Madkhali… - Updates in …, 2017 - books.google.com
Gallbladder cancer (GBC) is a rare but fatal disease with an incidence of less than 5000
new cases per year in the United States. Less than 20% of GBC cases are diagnosed …

Distal Cholangiocarcinoma

AA Madkhali, F Al-Alem - Bile Duct Cancer, 2019 - books.google.com
Cholangiocarcinoma arises from the epithelial lining of the biliary tree. It accounts for
approximately 3% of all gastrointestinal malignancies. This chapter looks at the new advances that …

Preoperative Selection and Optimization for Liver Resection in Colorectal Cancer Liver Metastases

A Madkhali, F Alalem, G Aljuhani, A Alsharaabi… - Current Colorectal …, 2018 - Springer
Purpose of Review Colorectal cancer is the third most common cancer in incidence and the
leading cause of death among males and females. Colorectal cancer liver metastatic …