User profiles for Faisal K. Alkholifi
Faisal AlkholifiPrince Sattam bin Abdulaziz University Verified email at psau.edu.sa Cited by 161 |
[HTML][HTML] Dostarlimab an inhibitor of PD-1/PD-L1: A new paradigm for the treatment of cancer
FK Alkholifi, RM Alsaffar - Medicina, 2022 - mdpi.com
Immunomodulation checkpoints usually adopted by healthy cells by tumors might cause an
imbalance between host surveillance and tumor progression. Several tumors are incredibly …
imbalance between host surveillance and tumor progression. Several tumors are incredibly …
[HTML][HTML] Simultaneous determination of caffeine and paracetamol in commercial formulations using greener normal-phase and reversed-phase HPTLC methods: A …
There has been no assessment of the greenness of the described analytical techniques for
the simultaneous determination (SMD) of caffeine and paracetamol. As a result, in …
the simultaneous determination (SMD) of caffeine and paracetamol. As a result, in …
[HTML][HTML] Protective Effect of Beta-Carotene against Myeloperoxidase- Mediated Oxidative Stress and Inflammation in Rat Ischemic Brain Injury
Oxidative stress and inflammatory reaction play critical roles in ischemia/reperfusion (I/R)
injury in the brain. β-carotene (βCAR) is a naturally occurring pigment present in fruits and …
injury in the brain. β-carotene (βCAR) is a naturally occurring pigment present in fruits and …
[HTML][HTML] The cardioprotective effect of Corosolic Acid in the Diabetic rats: A possible mechanism of the PPAR-γ pathway
The study was conducted to determine whether corosolic acid could protect the myocardium
of diabetic rats from damage caused by isoproterenol (ISO) and, if so, how peroxisome …
of diabetic rats from damage caused by isoproterenol (ISO) and, if so, how peroxisome …
[HTML][HTML] Chlorogenic acid restores ovarian functions in mice with letrozole-induced polycystic ovarian syndrome via modulation of adiponectin receptor
…, S Sofi, YF Jamous, MF Khan, FK Alkholifi… - Biomedicines, 2023 - mdpi.com
Around the world, polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic
condition that typically affects 6–20% of females. Our study’s major goal was to examine how …
condition that typically affects 6–20% of females. Our study’s major goal was to examine how …
[HTML][HTML] Formulation of genistein-hp β cyclodextrin-poloxamer 188 ternary inclusion complex: Solubility to cytotoxicity assessment
…, NK Alruwaili, SS Imam, OA Alsaidan, FK Alkholifi… - Pharmaceutics, 2021 - mdpi.com
The current study was designed to prepare the inclusion complex Genistein (GS) using
Hydroxypropyl β cyclodextrin (HP β CD) and poloxamer 188 (PL 188). The binary inclusion …
Hydroxypropyl β cyclodextrin (HP β CD) and poloxamer 188 (PL 188). The binary inclusion …
[HTML][HTML] Determination of Chemical Composition, In Vitro and In Silico Evaluation of Essential Oil from Leaves of Apium graveolens Grown in Saudi Arabia
The aim of this study was to explore the composition and evaluate the in silico and in vitro
antioxidants and antimicrobial and anti-inflammatory effects of Apium graveolens var. dulce …
antioxidants and antimicrobial and anti-inflammatory effects of Apium graveolens var. dulce …
[HTML][HTML] Phospholipid-based topical nano-hydrogel of Mangiferin: enhanced topical delivery and improved dermatokinetics
Mangiferin is a herbal drug that has proven anticancer potential. Owing to its lower aqueous
solubility and poor oral bioavailability, the full pharmacological potential of this bioactive …
solubility and poor oral bioavailability, the full pharmacological potential of this bioactive …
Exploring the efficacy and contribution of Dupilumab in asthma management
RM Alsaffar, FK Alkholifi - Molecular Immunology, 2022 - Elsevier
IgG4 monoclonal antibody Dupilumab binds to the alpha chain (IL4R) of both types of the
ligand-binding domains (IL4R/ IL13R1; equally IL4 and IL13 specific) of the IL-4 receptor. The …
ligand-binding domains (IL4R/ IL13R1; equally IL4 and IL13 specific) of the IL-4 receptor. The …
[HTML][HTML] Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model
Myocardial infarction (MI) continues to be an important issue in healthcare systems worldwide,
leading to high rates of morbidity and mortality. Despite ongoing efforts towards the …
leading to high rates of morbidity and mortality. Despite ongoing efforts towards the …