User profiles for Faisal K. Alkholifi

Faisal Alkholifi

Prince Sattam bin Abdulaziz University
Verified email at psau.edu.sa
Cited by 161

[HTML][HTML] Dostarlimab an inhibitor of PD-1/PD-L1: A new paradigm for the treatment of cancer

FK Alkholifi, RM Alsaffar - Medicina, 2022 - mdpi.com
Immunomodulation checkpoints usually adopted by healthy cells by tumors might cause an
imbalance between host surveillance and tumor progression. Several tumors are incredibly …

[HTML][HTML] Simultaneous determination of caffeine and paracetamol in commercial formulations using greener normal-phase and reversed-phase HPTLC methods: A …

…, A Ali, MH Alqarni, AI Foudah, TM Aljarba, FK Alkholifi… - Molecules, 2022 - mdpi.com
There has been no assessment of the greenness of the described analytical techniques for
the simultaneous determination (SMD) of caffeine and paracetamol. As a result, in …

[HTML][HTML] Protective Effect of Beta-Carotene against Myeloperoxidase- Mediated Oxidative Stress and Inflammation in Rat Ischemic Brain Injury

…, GA Soliman, HA Ogaly, FK Alkholifi… - Antioxidants, 2022 - mdpi.com
Oxidative stress and inflammatory reaction play critical roles in ischemia/reperfusion (I/R)
injury in the brain. β-carotene (βCAR) is a naturally occurring pigment present in fruits and …

[HTML][HTML] The cardioprotective effect of Corosolic Acid in the Diabetic rats: A possible mechanism of the PPAR-γ pathway

FK Alkholifi, S Devi, HS Yusufoglu, A Alam - Molecules, 2023 - mdpi.com
The study was conducted to determine whether corosolic acid could protect the myocardium
of diabetic rats from damage caused by isoproterenol (ISO) and, if so, how peroxisome …

[HTML][HTML] Chlorogenic acid restores ovarian functions in mice with letrozole-induced polycystic ovarian syndrome via modulation of adiponectin receptor

…, S Sofi, YF Jamous, MF Khan, FK Alkholifi… - Biomedicines, 2023 - mdpi.com
Around the world, polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic
condition that typically affects 6–20% of females. Our study’s major goal was to examine how …

[HTML][HTML] Formulation of genistein-hp β cyclodextrin-poloxamer 188 ternary inclusion complex: Solubility to cytotoxicity assessment

…, NK Alruwaili, SS Imam, OA Alsaidan, FK Alkholifi… - Pharmaceutics, 2021 - mdpi.com
The current study was designed to prepare the inclusion complex Genistein (GS) using
Hydroxypropyl β cyclodextrin (HP β CD) and poloxamer 188 (PL 188). The binary inclusion …

[HTML][HTML] Determination of Chemical Composition, In Vitro and In Silico Evaluation of Essential Oil from Leaves of Apium graveolens Grown in Saudi Arabia

…, MH Alqarni, A Alam, MA Salkini, P Alam, FK Alkholifi… - Molecules, 2021 - mdpi.com
The aim of this study was to explore the composition and evaluate the in silico and in vitro
antioxidants and antimicrobial and anti-inflammatory effects of Apium graveolens var. dulce …

[HTML][HTML] Phospholipid-based topical nano-hydrogel of Mangiferin: enhanced topical delivery and improved dermatokinetics

FK Alkholifi, A Alam, AI Foudah, HS Yusufoglu - Gels, 2023 - mdpi.com
Mangiferin is a herbal drug that has proven anticancer potential. Owing to its lower aqueous
solubility and poor oral bioavailability, the full pharmacological potential of this bioactive …

Exploring the efficacy and contribution of Dupilumab in asthma management

RM Alsaffar, FK Alkholifi - Molecular Immunology, 2022 - Elsevier
IgG4 monoclonal antibody Dupilumab binds to the alpha chain (IL4R) of both types of the
ligand-binding domains (IL4R/ IL13R1; equally IL4 and IL13 specific) of the IL-4 receptor. The …

[HTML][HTML] Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model

AH Aodah, S Devi, FK Alkholifi, HS Yusufoglu… - Molecules, 2023 - mdpi.com
Myocardial infarction (MI) continues to be an important issue in healthcare systems worldwide,
leading to high rates of morbidity and mortality. Despite ongoing efforts towards the …