User profiles for Gan Shen

Gan Shen

University of California, Santa Cruz
Verified email at ucsc.edu
Cited by 24

[HTML][HTML] Tumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapy

JH Xu, SL Hu, GD Shen, G Shen - Cancer cell international, 2016 - Springer
Objectives Paclitaxel (PTX) is frequently used in the clinical treatment of solid tumors. But
the PTX-resistance is a great obstacle in cancer treatment. Exploration of the mechanisms of …

[HTML][HTML] Relationship between epithelial cell adhesion molecule (EpCAM) overexpression and gastric cancer patients: A systematic review and meta-analysis

M Dai, F Yuan, C Fu, G Shen, S Hu, G Shen - PloS one, 2017 - journals.plos.org
Objectives The epithelial cell adhesion molecule (EpCAM) is one of the most commonly used
markers of cancer stem cells (CSCs), but the clinical and prognostic significance of EpCAM …

Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanism

M Cheng, L Qian, G Shen, G Bian, T Xu, W Xu, G Shen… - Cancer research, 2014 - AACR
Commensal bacteria are crucial to maintain immune homeostasis in mucosal tissues and
disturbances in their ecology can affect disease susceptibility. Here, we report evidence that …

Melatonin protects against alcoholic liver injury by attenuating oxidative stress, inflammatory response, and apoptosis

S Hu, S Yin, X Jiang, D Huang, G Shen - European journal of pharmacology, 2009 - Elsevier
Melatonin is reported to exhibit a wide variety of biological effects, including antioxidant and
anti-inflammatory. Previous studies show that melatonin has a protective role in different …

Intra‐articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF‐2α

…, L Cai, Y Zhang, L Cui, G Shen - Journal of Orthopaedic …, 2015 - Wiley Online Library
We investigated the feasibility of the intra‐articular injection of resveratrol for preventing the
progression of existing cartilage degeneration in a mouse model of osteoarthritis (OA). The …

Clinical practice guidelines for hypertension in China: a systematic review of the methodological quality

Y Chen, S Hu, L Wu, X Fang, W Xu, G Shen - BMJ open, 2015 - bmjopen.bmj.com
Objective Clinical practice guidelines (CPGs) provide clinicians with specific recommendations
for practice, but due to the increasing number of CPGs developed by diverse …

Ape-gan: Adversarial perturbation elimination with gan

S Shen, G Jin, K Gao, Y Zhang - arXiv preprint arXiv:1707.05474, 2017 - arxiv.org
GAN to generate clean examples from adversarial examples. Meanwhile, SRGAN[13], the
successful application of GAN on … In addition, GAN and its connection to our method will be …

Paeonol, the main active principles of Paeonia moutan, ameliorates alcoholic steatohepatitis in mice

S Hu, G Shen, W Zhao, F Wang, X Jiang… - Journal of …, 2010 - Elsevier
AIM OF STUDY: Paeonol, a major phenolic component of Moutan Cortex, is traditionally
used as a Chinese herbal medicine in various diseases including hepatitis. Evidence shows …

Haschor: Functional choreographic programming for all (functional pearl)

G Shen, S Kashiwa, L Kuper - Proceedings of the ACM on Programming …, 2023 - dl.acm.org
Choreographic programming is an emerging paradigm for programming distributed systems.
In choreographic programming, the programmer describes the behavior of the entire …

Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma

SL Hu, XY Kong, ZD Cheng, YB Sun, G Shen… - Tumori …, 2010 - journals.sagepub.com
Aims and background Transcriptional silencing induced by hypermethylation of CpG
islands in the promoter regions of genes is believed to be an important mechanism of …