User profiles for Gehan A. Hegazy
 | Gehan A. HegazyAssociate Professor in Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University … Verified email at kau.edu.sa Cited by 671 |
Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory …
AH Abadi, GH Hegazy, AA El-Zaher - Bioorganic & medicinal chemistry, 2005 - Elsevier
Six derivatives of the general formula 2- or 4-(7-trifluoromethylquinolin-4-ylamino) benzoic
acid N′-(nitrooxyacetyl or propionyl) hydrazide and an oxime of the formula 1-[4-(7-…
acid N′-(nitrooxyacetyl or propionyl) hydrazide and an oxime of the formula 1-[4-(7-…
Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities
HA Bashmail, AA Alamoudi, A Noorwali, GA Hegazy… - Scientific reports, 2018 - nature.com
The use of anti-cancer adjuvant therapy is rationalized by potentiating the efficacy, and/or
protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally …
protecting from major side effects of chemotherapeutics. Thymoquinone (TQ) is a naturally …
[PDF][PDF] The role of Acacia Arabica extract as an antidiabetic, antihyperlipidemic, and antioxidant in streptozotocin-induced diabetic rats
Objectives: To investigate the role of Acacia Arabica extract as a hypoglycemic, antihyperlipidemic,
and antioxidant agent in streptozotocin-induced diabetic rats. Methods: his is an …
and antioxidant agent in streptozotocin-induced diabetic rats. Methods: his is an …
Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents
Several derivatives with a quinoline scaffold and a flexible, semi-flexible or rigid side chains
at position 8 of the quinoline ring were synthesized and assessed for their in vitro activity …
at position 8 of the quinoline ring were synthesized and assessed for their in vitro activity …
Prophylactic role of coenzyme Q10 and Cynara scolymus L on doxorubicin-induced toxicity in rats: Biochemical and immunohistochemical study
Prophylactic role of coenzyme Q10 and Cynara scolymus L on d... : Indian Journal of
Pharmacology Prophylactic role of coenzyme Q10 and Cynara scolymus L on doxorubicin-induced …
Pharmacology Prophylactic role of coenzyme Q10 and Cynara scolymus L on doxorubicin-induced …
Protective role of antioxidants on thioacetamide-induced acute hepatic encephalopathy: biochemical and ultrastructural study
Thioacetamide (TAA) has been used in development of animal models of acute hepatic
encephalopathy (AHE). This experimental study was designed to evaluate effects of oral …
encephalopathy (AHE). This experimental study was designed to evaluate effects of oral …
Protective role of CoQ10 or L-carnitine on the integrity of the myocardium in doxorubicin induced toxicity
Doxorubicin (DOX) is a chemotherapeutic agent used for treatment of different cancers and
its clinical usage is hindered by the oxidative injury-related cardiotoxicity. This work aims to …
its clinical usage is hindered by the oxidative injury-related cardiotoxicity. This work aims to …
Thymoquinone enhances paclitaxel anti-breast cancer activity via inhibiting tumor-associated stem cells despite apparent mathematical antagonism
HA Bashmail, AA Alamoudi, A Noorwali, GA Hegazy… - Molecules, 2020 - mdpi.com
Thymoquinone (TQ) has shown substantial evidence for its anticancer effects. Using human
breast cancer cells, we evaluated the chemomodulatory effect of TQ on paclitaxel (PTX). TQ …
breast cancer cells, we evaluated the chemomodulatory effect of TQ on paclitaxel (PTX). TQ …
Synthesis, anticonvulsant activity and molecular modeling study of some new hydrazinecarbothioamide, benzenesulfonohydrazide, and phenacylacetohydrazide …
HSA Al-Salem, GH Hegazy, KEH El-Taher… - Bioorganic & Medicinal …, 2015 - Elsevier
A new series of quinazoline analogues was designed and synthesized to get the target
compounds 18–21, 30–41, 46–53, and 57–76. The Obtained compounds were evaluated for …
compounds 18–21, 30–41, 46–53, and 57–76. The Obtained compounds were evaluated for …
Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic …
GH Hegazy, HI Ali - Bioorganic & medicinal chemistry, 2012 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently associated with gastric mucosal
and renal adverse reactions, related to inhibition of cyclooxygenase1 (Cox1) in tissues …
and renal adverse reactions, related to inhibition of cyclooxygenase1 (Cox1) in tissues …
