A valuable antigen detection method for diagnosis of acute hepatitis E

GP Wen, ZM Tang, F Yang, K Zhang… - Journal of clinical …, 2015 - Am Soc Microbiol
Hepatitis E virus (HEV) is a serious public health problem. The commonly used tests that are
specific for current HEV infection diagnosis include the detection of anti-HEV IgM and HEV …

[HTML][HTML] Case Report: Chronic hepatitis E in a hematopoietic stem cell transplant recipient: The first report of hepatitis E virus genotype 4 causing chronic infection in a …

…, L Jiang, D Ying, W Tian, M Zhang, G Wen… - Frontiers in …, 2022 - frontiersin.org
Hepatitis E virus (HEV) is one of the most important public health issues around the world,
and chronic HEV infection has been reported in immunosuppressed individuals. This study …

Redeveloping antigen detection kits for the diagnosis of rat hepatitis E virus

…, S Guo, Y Huang, S Wu, Z Tang, G Wen… - Journal of Clinical …, 2023 - Am Soc Microbiol
The emergence of Rocahepevirus ratti [species HEV ratti (r HEV)] as a causative agent of
hepatitis E in humans presents a new potential threat to global public health. The R. ratti …

[HTML][HTML] Quantitative evaluation of protective antibody response induced by hepatitis E vaccine in humans

GP Wen, L He, ZM Tang, SL Wang, X Zhang… - Nature …, 2020 - nature.com
Efficacy evaluation through human trials is crucial for advancing a vaccine candidate to
clinics. Next-generation sequencing (NGS) can be used to quantify B cell repertoire response …

[HTML][HTML] A secreted form of the hepatitis E virus ORF2 protein: design strategy, antigenicity and immunogenicity

Z Chen, S Guo, G Li, D Ying, G Wen, M Fang, Y Wang… - Viruses, 2022 - mdpi.com
Hepatitis E virus (HEV) is an important public health burden worldwide, causing approximately
20 million infections and 70,000 deaths annually. The viral capsid protein is encoded by …

A novel linear neutralizing epitope of hepatitis E virus

ZM Tang, M Tang, M Zhao, GP Wen, F Yang, W Cai… - Vaccine, 2015 - Elsevier
Hepatitis E virus (HEV) is a serious public health problem that causes acute hepatitis in
humans and is primarily transmitted through fecal and oral routes. The major anti-HEV antibody …

Long-term HEV carriers without antibody seroconversion among eligible immunocompetent blood donors

GP Wen, CR Chen, XY Song, ZM Tang… - Emerging Microbes & …, 2018 - Taylor & Francis
Hepatitis E virus (HEV) is emerging as a potential threat to the safety of blood transfusions.
In many countries and regions endemic for HEV, such as China, blood donors are not …

Profile of clinical characteristics and serologic markers of sporadic hepatitis E in a community cohort study

ZM Tang, GP Wen, D Ying, SL Wang, C Liu… - Emerging Microbes & …, 2023 - Taylor & Francis
Hepatitis E virus (HEV) is a pathogen of global significance, but the value of HEV-related
markers in the diagnosis of hepatitis E remains controversial. Previous studies on hepatitis E …

[HTML][HTML] Prevalence of hepatitis E virus and its associated outcomes among pregnant women in China

GP Wen, MM Wang, ZM Tang, C Liu, ZH Yu, Z Wang… - Pathogens, 2023 - mdpi.com
Hepatitis E virus (HEV) is a significant public health concern worldwide. Pregnant women are
at high risk of severe HEV infection. Various adverse outcomes in pregnant women related …

[HTML][HTML] Homologous booster immunization with an inactivated vaccine induced robust antibody response in healthcare workers: A retrospective study

GP Wen, M Zhu, LR Li, XJ Li, HM Ye… - Frontiers in …, 2023 - frontiersin.org
Coronavirus Disease 2019 (Covid-19) severely impacted the health, society, and economy
around the world. With declining protective efficacy of primary vaccination and the spread of …