Background Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have demonstrated
promise in treating a variety of advanced cancers; however, little is known regarding …

Poly (ADP-ribose) polymerase (PARP) inhibitors have demonstrated great promise for
treating cancers with homologous recombination (HR) defects, such as germline BRCA1/2 …

The efficacy of current treatment regimens for pancreatic cancer (PC) remains unsatisfactory.
In recent years, immune checkpoint blockade (ICB) therapy has shown promising anti-…

A loop-mediated isothermal amplification (LAMP) assay was developed and validated for
the specific detection of Salmonella in food. The assay used specifically designed primers to …

The efficacies of pembrolizumab and nivolumab have never been directly compared in a
real-world study. Therefore, we sought to retrospectively evaluate the objective response rate (…

Along with the speeding up of Chinese urbanization process, the contradiction between
urban land demand and supply had increased significantly, more and more underground …

Background: Targeting immune checkpoints represents an immense breakthrough in cancer
therapeutics. The prognostic value of hemoglobin (Hb) has been investigated in many …

Background: MicroRNAs miR-9-3 and miR-193a have recently been found to be hypermethylated
in a variety of non-small cell lung cancer (NSCLC) cells and primary human tumors. …

Clinical studies have shown that statin use may alter the risk of lung cancer. However, these
studies yielded different results. To quantify the association between statin use and risk of …

Background: Cutaneous adverse events (AEs) have been positively associated with immune
checkpoint inhibitor (ICI) efficacy in patients with melanoma, but little is known regarding …