The toxicity of gentamicin (GEN) in the kidney seems to relate to the generation of reactive
oxygen species (ROS). Caffeic acid phenethyl ester (CAPE) has been demonstrated to have …

Abstract: Cisplatin [cis‐diaminedichloroplatinum(II), CDDP] is a widely used antineoplastic
drug. However, it has major side‐effects such as acute tubular necrosis (ATN). There are a …

Several studies have well confirmed the contribution of oxidative stress in the pathogenesis
of methotrexate (MTX)-induced damage in the small intestine. Many agents have been tried …

The toxicity of aminoglycosides including gentamicin (GEN), the most widely used drug in
this category, is believed to be related to the generation of reactive oxygen species (ROS) in …

In this study, the authors aimed to investigate the role of oxidative stress on the hepatic damage
caused by methotrexate (MTX) and the possible protective effects of β-carotene against …

Free radicals, calcium overloading and loss of membrane phospholipids play an important
role in the development of ischemia/reperfusion (I/R) injury. Melatonin is a well-known …

Immunosuppressive drugs used in the transplantation period are generally defined as
induction and maintenance therapy. The use of immunosuppressants, which are particularly …

Background The aging process is not univocal, both body and brain age. Neurological disorders
are a major cause of disability and death worldwide. According to the Global Burden of …

Cardiovascular diseases are known to be the most fatal diseases worldwide. Ischaemia/reperfusion
(I/R) injury is at the centre of the pathology of the most common cardiovascular …

OBJECTIVE: To investigate the effect of β-carotene against testicular injury induced by
methotrexate (MTX). DESIGN: Experimental study. SETTING: Animal and histology laboratory at …