User profiles for Hongbo Chen

Hongbo Chen

Paediatrics,Union Hospital, Tongji Medical College, Huazhong University of Science and …
Verified email at hust.edu.cn
Cited by 2339

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

…, S Das, S Saberi, Y Li, J Hitomi, H Zhu, H Chen… - Science, 2016 - science.org
Mutations in the optineurin (OPTN) gene have been implicated in both familial and sporadic
amyotrophic lateral sclerosis (ALS). However, the role of this protein in the central nervous …

Metal-free carbon materials-catalyzed sulfate radical-based advanced oxidation processes: a review on heterogeneous catalysts and applications

…, J Wei, X Liu, J Yang, L Luo, J Zhang, H Chen, H Chen… - Chemosphere, 2017 - Elsevier
In recent years, advanced oxidation processes (AOPs), especially sulfate radical based AOPs
have been widely used in various fields of wastewater treatment due to their capability and …

Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance

H Zhu, H Chen, X Zeng, Z Wang, X Zhang, Y Wu… - Biomaterials, 2014 - Elsevier
We report a strategy to make use of poly(lactic-co-glycolic acid) nanoparticle (PLGA NPs)
for co-delivery of docetaxel (DTX) as a model anticancer drug together with vitamin E TPGS. …

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

…, X Fang, X Zhang, F Zhang, H Chen… - Proceedings of the …, 2014 - National Acad Sciences
Expression of receptor for hyaluronan-mediated motility (RHAMM), a breast cancer susceptibility
gene, is tightly controlled in normal tissues but elevated in many tumors, contributing to …

[PDF][PDF] TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging

D Xu, T Jin, H Zhu, H Chen, D Ofengeim, C Zou… - Cell, 2018 - cell.com
Aging is a major risk factor for both genetic and sporadic neurodegenerative disorders.
However, it is unclear how aging interacts with genetic predispositions to promote …

A reference human genome dataset of the BGISEQ-500 sequencer

…, Y Xuan, C Geng, Y Li, H Lu, S Qu, X Mei, H Chen… - …, 2017 - academic.oup.com
Background: BGISEQ-500 is a new desktop sequencer developed by BGI. Using DNA
nanoball and combinational probe anchor synthesis developed from Complete Genomics™ …

Application of protein-based films and coatings for food packaging: A review

H Chen, J Wang, Y Cheng, C Wang, H Liu, H Bian… - Polymers, 2019 - mdpi.com
As the IV generation of packaging, biopolymers, with the advantages of biodegradability,
process ability, combination possibilities and no pollution to food, have become the leading …

Ultrasound aided photochemical synthesis of Ag loaded TiO2 nanotube arrays to enhance photocatalytic activity

L Sun, J Li, C Wang, S Li, Y Lai, H Chen… - Journal of Hazardous …, 2009 - Elsevier
This work presents a novel approach for preparing TiO 2 nanotube array photocatalyst loaded
with highly dispersed Ag nanoparticles through an ultrasound aided photochemical route. …

Free nitrous acid serving as a pretreatment method for alkaline fermentation to enhance short-chain fatty acid production from waste activated sludge

J Zhao, D Wang, X Li, Q Yang, H Chen, Y Zhong… - Water research, 2015 - Elsevier
Alkaline condition (especially pH 10) has been demonstrated to be a promising method for
short-chain fatty acid (SCFA) production from waste activated sludge anaerobic fermentation, …

Photoelectrocatalytic properties of Ag nanoparticles loaded TiO2 nanotube arrays prepared by pulse current deposition

K Xie, L Sun, C Wang, Y Lai, M Wang, H Chen, C Lin - Electrochimica Acta, 2010 - Elsevier
A pulse current deposition technique was adopted to construct highly dispersed Ag nanoparticles
on TiO 2 nanotube arrays which were prepared by the electrochemical anodization. …