User profiles for Hua Li

Hua-Bin Li

- Verified email at mail.sysu.edu.cn - Cited by 39654

Hua Li

- Verified email at alumni.brown.edu - Cited by 6249

Hua-bing Li

- Verified email at yale.edu - Cited by 4122

[HTML][HTML] Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

…, Y Xu, M Li, X Li, M Zheng, L Chen, H Li - … Pharmaceutica Sinica B, 2020 - Elsevier
SARS-CoV-2 has caused tens of thousands of infections and more than one thousand deaths.
There are currently no registered therapies for treating coronavirus infections. Because of …

[HTML][HTML] Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons

H Li, J Chen, W Wu, T Fagaly, L Zhou, W Yuan… - Cell, 1999 - cell.com
The olfactory bulb plays a central role in olfactory information processing through its connections
with both peripheral and cortical structures. Axons projecting from the olfactory bulb to …

Solution NMR studies of the Aβ (1− 40) and Aβ (1− 42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

L Hou, H Shao, Y Zhang, H Li, NK Menon… - Journal of the …, 2004 - ACS Publications
The pathogenesis of Alzheimer's disease is characterized by the aggregation and fibrillation
of the 40-residue Aβ(1−40) and 42-residue Aβ(1−42) peptides into amyloid plaques. The …

[HTML][HTML] A chromosome conformation capture ordered sequence of the barley genome

…, S Cao, B Chapman, F Dai, Y Han, H Li, X Li… - Nature, 2017 - nature.com
Cereal grasses of the Triticeae tribe have been the major food source in temperate regions
since the dawn of agriculture. Their large genomes are characterized by a high content of …

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and …

H Li, V Papadopoulos - Endocrinology, 1998 - academic.oup.com
In steroid-synthesizing cells, like the MA-10 mouse tumor Leydig cells, the peripheral-type
benzodiazepine receptor (PBR) is an outer mitochondrial membrane protein involved in the …

[HTML][HTML] Biological activities of polyphenols from grapes

EQ Xia, GF Deng, YJ Guo, HB Li - International journal of molecular …, 2010 - mdpi.com
The dietary consumption of grape and its products is associated with a lower incidence of
degenerative diseases such as cardiovascular disease and certain types of cancers. Most …

[HTML][HTML] Ferroptosis: mechanisms and links with diseases

H Yan, T Zou, Q Tuo, S Xu, H Li, AA Belaidi… - Signal transduction and …, 2021 - nature.com
Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis,
autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by the …

A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates

GR Chichili, L Huang, H Li, S Burke, L He… - Science translational …, 2015 - science.org
Current therapies for acute myeloid leukemia (AML) are largely ineffective, and AML
patients may benefit from targeted immunotherapy approaches. MGD006 is a bispecific …

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

HB Li, J Tong, S Zhu, PJ Batista, EE Duffy, J Zhao… - Nature, 2017 - nature.com
N 6 -methyladenosine (m 6 A) is the most common and abundant messenger RNA
modification, modulated by ‘writers’, ‘erasers’ and ‘readers’ of this mark 1 , 2 . In vitro data have …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in biomedical
areas including bioimaging, biodetection, and drug delivery. As an emerging field, DNA …