The HMGB1–TLR4 axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte apoptosis
HS Ding, J Yang, P Chen, J Yang, SQ Bo, JW Ding… - Gene, 2013 - Elsevier
Toll-like receptor 4 (TLR4) and its ligand high mobility group box 1 (HMGB1), are known for
playing central roles in ischemia–reperfusion injury in myocardium. However, the detailed …
playing central roles in ischemia–reperfusion injury in myocardium. However, the detailed …
[HTML][HTML] Radioprotective 105 kDa protein attenuates ischemia/reperfusion-induced myocardial apoptosis and autophagy by inhibiting the activation of the TLR4/NF-κB …
…, JW Ding, S Li, H Wu, HS Ding - International …, 2016 - spandidos-publications.com
Toll-like receptor 4 (TLR4) serves as an important inducer of apoptotic and autophagic responses
in myocardial ischemia/reperfusion (I/R) injury (MIRI). Radioprotective 105 kDa protein …
in myocardial ischemia/reperfusion (I/R) injury (MIRI). Radioprotective 105 kDa protein …
[HTML][HTML] S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton
C Zhang, N Yang, C Yang, H Ding, C Luo, Y Zhang… - PloS one, 2009 - journals.plos.org
Background Deregulation of the phosphatidylinositol 3-kinases (PI3K)/Akt/mammalian
target of rapamycin (mTOR) pathway plays a central role in tumor formation and progression, …
target of rapamycin (mTOR) pathway plays a central role in tumor formation and progression, …
High mobility box 1 mediates neutrophil recruitment in myocardial ischemia–reperfusion injury through toll like receptor 4-related pathway
HS Ding, J Yang, FL Gong, J Yang, JW Ding, S Li… - Gene, 2012 - Elsevier
This study aimed to explore the role of high mobility box 1 (HMGB1) and its receptor toll like
receptor 4 (TLR4) on neutrophils in myocardial ischemia reperfusion (I/R) injury. We …
receptor 4 (TLR4) on neutrophils in myocardial ischemia reperfusion (I/R) injury. We …
[HTML][HTML] MiR-33 promotes myocardial fibrosis by inhibiting MMP16 and stimulating p38 MAPK signaling
Z Chen, HS Ding, X Guo, JJ Shen, D Fan, Y Huang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Myocardial fibrosis occurs in the late stages of many cardiovascular diseases, and appears
to be stimulated by various microRNAs (miRNAs). We previously found that miR-33 may …
to be stimulated by various microRNAs (miRNAs). We previously found that miR-33 may …
Fluvastatin attenuated ischemia/reperfusion-induced autophagy and apoptosis in cardiomyocytes through down-regulation HMGB1/TLR4 signaling pathway
HS Ding, J Yang, J Yang, X Guo, YH Tang… - Molecular Biology …, 2021 - Springer
Fluvastatin, a traditional fat-decreasing drug, is widely used for curing cardiovascular disease.
Previous reports demonstrated that fluvastatin pretreatment protected against myocardial …
Previous reports demonstrated that fluvastatin pretreatment protected against myocardial …
[HTML][HTML] High mobility group box 1 and kidney diseases
P Zhu, L Xie, HS Ding, Q Gong… - International …, 2013 - spandidos-publications.com
High mobility group box 1 (HMGB1), a non-histone DNA-binding protein, regulates
nucleosome function and transcription in the nuclei of all metazoans and plants. However, …
nucleosome function and transcription in the nuclei of all metazoans and plants. However, …
High mobility group box-1 and cardiovascular diseases.
HS Ding, J Yang - Saudi medical journal, 2010 - europepmc.org
… Ding HS , … Ding HS, Yang J, Yang J, Guo X, Tang YH, Huang Y, Chen Z, Fan ZX, Huang CX …
Interleukin-17 contributes to cardiovascular diseases
HS Ding, J Yang, J Yang, JW Ding, P Chen… - Molecular Biology …, 2012 - Springer
Interleukin (IL)-17 (also known as IL-17A), as the signature cytokine of the newly described
T helper 17 (Th17) cell population, is the founding member of a new subclass of cytokines …
T helper 17 (Th17) cell population, is the founding member of a new subclass of cytokines …
Panaxynol ameliorates cardiac ischemia/reperfusion injury by suppressing NLRP3-induced pyroptosis and apoptosis via HMGB1/TLR4/NF-κB axis
HS Ding, Y Huang, JF Qu, YJ Wang, ZY Huang… - International …, 2023 - Elsevier
Background and purpose Panaxynol (PNN) is a common natural minor component in
Umbelliferae plants. Many clinical studies have shown that PNN exhibits nutritional value and anti-…
Umbelliferae plants. Many clinical studies have shown that PNN exhibits nutritional value and anti-…
