Neuroprotective effects of resveratrol against traumatic brain injury in immature rats

Ü Sönmez, A Sönmez, G Erbil, I Tekmen, B Baykara - Neuroscience letters, 2007 - Elsevier
Childhood trauma resulting in traumatic brain injury (TBI) due to accidents and abuse is the
major cause of death and dysfunction in the young. Since there are no approved specific …

Effective topical delivery systems for corticosteroids: dermatological and histological evaluations

…, M Nenni, H Gürer Orhan, S Özbal, I Tekmen… - Drug …, 2016 - Taylor & Francis
Atopic dermatitis (AD) is a chronic and relapsing skin disease with severe eczematous
lesions. Long-term topical corticosteroid treatment can induce skin atrophy, hypopigmentation …

[HTML][HTML] The Effects of α-Lipoic Acid against Testicular Ischemia-Reperfusion Injury in Rats

S Ozbal, BU Ergur, G Erbil, I Tekmen… - The Scientific World …, 2012 - hindawi.com
Testicular torsion is one of the urologic emergencies occurring frequently in neonatal and
adolescent period. Testis is sensitive to ischemia-reperfusion injury, and, therefore, ischemia …

Wound healing effects of collagen-laminin dermal matrix impregnated with resveratrol loaded hyaluronic acid-DPPC microparticles in diabetic rats

…, I Eroglu, N Tsapis, G Gokce, I Tekmen… - European Journal of …, 2017 - Elsevier
An alternative formulation for the treatment of diabetic foot wounds that heal slowly is a
requirement in pharmaceutical field. The aim of this study was to develop a dermal matrix …

The protective effects of carnosine and melatonin in ischemia-reperfusion injury in the rat liver

B Baykara, I Tekmen, C Pekcetin, C Ulukus, P Tuncel… - Acta histochemica, 2009 - Elsevier
The reperfusion following liver ischemia results in hepatocyte damage and apoptosis. The
aim of this study was to investigate the effects of two antioxidant agents, carnosine and …

[HTML][HTML] In vivo assessment of clobetasol propionate-loaded lecithin-chitosan nanoparticles for skin delivery

T Şenyiğit, F Sonvico, A Rossi, I Tekmen… - International Journal of …, 2016 - mdpi.com
The aim of this work was to assess in vivo the anti-inflammatory efficacy and tolerability of
clobetasol propionate (CP) loaded lecithin/chitosan nanoparticles incorporated into chitosan …

Deoxycholate hydrogels of betamethasone-17-valerate intended for topical use: in vitro and in vivo evaluation

T Şenyiğit, I Tekmen, Ü Sönmez, P Santi… - International journal of …, 2011 - Elsevier
The aim of this study was to evaluate the suitability of sodium-deoxycholate (Na-DOC) gels
containing betamethasone-17-valerate (BMV) for topical application. The gels were …

[HTML][HTML] Protective effects of resveratrol against chronic immobilization stress on testis

G Bitgul, I Tekmen, D Keles, G Oktay - … Scholarly Research Notices, 2013 - hindawi.com
Objective. The aim of this study was to investigate protective effects of resveratrol, a strong
antioxidant, against possible negative effects of chronic immobilization stress on testes of …

[HTML][HTML] Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro

…, I Bozkurt, O Guzeloglu-Kayisli, B Sozen, I Tekmen… - Fertility and …, 2014 - Elsevier
Objective To study the effect of increased endoplasmic reticulum (ER) stress as a major
nongenomic mechanism for arrested blastocyst development. Design Cell and animal study. …

[HTML][HTML] Effect of dexmedetomidine on acute lung injury in experimental ischemia-reperfusion model

…, R Abdullayev, A Ustaoğlu, I Tekmen… - Revista Brasileira de …, 2017 - SciELO Brasil
Purpose: Ischemia-reperfusion injury is one of the consequences of tourniquet application
for extremity surgery. The aim of the study was to establish the effect of dexmedetomidine on …