Tertiary lymphoid organs (TLOs) develop at ectopic sites within chronically inflamed tissues,
such as in autoimmunity and rejecting organ allografts. TLOs differ structurally from …

Background: A large number of COVID-19 patients reveal a marked decrease in their lymphocyte
counts—a condition that translates clinically into the state of immunodepression, which …

A synthetic human V L phage display library, created by the randomization of all
complementarity-determining regions (CDRs) in a V L scaffold, was panned against three test …

Background: Chemotherapy-related anemia is prevalent in up to 75% of patients, which
may arise due to hemolysis and eryptosis. Alpha-mangostin (α-MG) is a polyphenolic …

Chronic rejection of solid organ allografts remains the major cause of transplant failure.
Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, …

Deguelin (DGN), a retinoid isolated from many plants, exhibits a potent anticancer activity
against a wide spectrum of tumour cells. There is a dearth of evidence, however, regarding the …

Background: Abnormalities in fasting blood glucose (FBG) resulting in hypoglycemia (OG),
impaired fasting glycemia (IFG), or hyperglycemia (HG) arise from disordered metabolic …

Inflammation is pivotal to the pathogenesis of diabetes mellitus (DM), but pathological
alterations of the neutrophil–lymphocyte ratio (NLR), an emerging inflammatory index in DM …

Chemotherapy-related anemia is a major obstacle in anticancer therapy. Tamoxifen (TAM) is
an antiestrogen prescribed for breast cancer patients with hemolytic potential and apoptotic …

Tumor necrosis factor-related apoptosis-induced ligand (TRAIL) is a cytokine that initiates
apoptosis upon binding to death receptor 5 (DR5) on cancer cells. Small molecule TRAIL …