Role of AhR in positive regulation of cell proliferation and survival
J Yin, B Sheng, Y Qiu, K Yang, W Xiao… - Cell proliferation, 2016 - Wiley Online Library
The aryl hydrocarbon receptor (AhR) is an important nuclear transcription factor that is best
known for mediating toxic responses by adjusting numbers of metabolism‐related enzymes, …
known for mediating toxic responses by adjusting numbers of metabolism‐related enzymes, …
The role of hypoxia‐inducible factor 1‐alpha in inflammatory bowel disease
J Yin, Y Ren, K Yang, W Wang, T Wang… - Cell Biology …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) develops as a result of a combination of genetic
predisposition, dysbiosis of the gut microbiota, and environmental influences, which is mainly …
predisposition, dysbiosis of the gut microbiota, and environmental influences, which is mainly …
The protective roles of NLRP 6 in intestinal epithelial cells
J Yin, B Sheng, K Yang, L Sun, W Xiao… - Cell proliferation, 2019 - Wiley Online Library
The evolution of chronic inflammatory diseases is thought to be due to a combination of host
genetic variations and environmental factors that include the alteration of intestinal flora, …
genetic variations and environmental factors that include the alteration of intestinal flora, …
SCFAs induce autophagy in intestinal epithelial cells and relieve colitis by stabilizing HIF-1α
C Zhou, L Li, T Li, L Sun, J Yin, H Guan, L Wang… - Journal of Molecular …, 2020 - Springer
Hypoxia-inducible factor-1α (HIF-1α) is a critical regulator of barrier integrity during colonic
mucosal injury. Previous works have shown that the absence of autophagy is implicated in …
mucosal injury. Previous works have shown that the absence of autophagy is implicated in …
[HTML][HTML] Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway
…, K Yang, B Han, B Sheng, J Yin… - International …, 2018 - spandidos-publications.com
The pathogenesis of inflammatory bowel disease (IBD) is believed to be associated with the
abnormal expression of inflammatory factors. The aryl hydrocarbon receptor (AhR) is a …
abnormal expression of inflammatory factors. The aryl hydrocarbon receptor (AhR) is a …
Aryl hydrocarbon receptor activation in intestinal obstruction ameliorates intestinal barrier dysfunction via suppression of MLCK-MLC phosphorylation pathway
B Han, B Sheng, Z Zhang, A Pu, J Yin, Q Wang, K Yang… - Shock, 2016 - journals.lww.com
Background: Accumulating evidence suggests that the aryl hydrocarbon receptor (AhR) plays
an important role in the maintenance of the function of the intestinal barrier in patients with …
an important role in the maintenance of the function of the intestinal barrier in patients with …
Mutual regulation between butyrate and hypoxia‐inducible factor‐1α in epithelial cell promotes expression of tight junction proteins
J Yin, C Zhou, K Yang, Y Ren, Y Qiu, P Xu… - Cell biology …, 2020 - Wiley Online Library
Inflammatory bowel disease is a kind of multi‐aetiological chronic disease that is driven by
multidimensional factors. Hypoxia‐inducible factor‐1α (HIF‐1α) plays an important role in anti…
multidimensional factors. Hypoxia‐inducible factor‐1α (HIF‐1α) plays an important role in anti…
Aryl hydrocarbon receptor activation alleviates dextran sodium sulfate-induced colitis through enhancing the differentiation of goblet cells
J Yin, K Yang, C Zhou, P Xu, W Xiao, H Yang - … and biophysical research …, 2019 - Elsevier
Background The intestinal inflammation induces disruption of the intestinal barrier function
and leads to bacteria invasion. Accumulating evidences revealed that the aryl hydrocarbon …
and leads to bacteria invasion. Accumulating evidences revealed that the aryl hydrocarbon …
[HTML][HTML] Identification and verification of YBX3 and its regulatory gene HEIH as an oncogenic system: A multidimensional analysis in colon cancer
…, Z Li, W Wang, X Zhang, W Li, G Du, J Yin… - Frontiers in …, 2022 - frontiersin.org
The novel gene YBX3 is important for regulating translation and RNA catabolism and
encodes a protein with a highly conserved cold-shock domain. However, its pathogenic roles …
encodes a protein with a highly conserved cold-shock domain. However, its pathogenic roles …
[HTML][HTML] Antifungal treatment aggravates sepsis through the elimination of intestinal fungi
…, Y Chen, L Sun, P Xu, B Han, X Li, J Yin… - … Medicine and Cellular …, 2021 - hindawi.com
Prophylactic antifungal therapy is widely adopted clinically for critical patients and effective
in reducing the morbidity of invasive fungal infection and improves outcomes of those …
in reducing the morbidity of invasive fungal infection and improves outcomes of those …