Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

CM Metallo, PA Gameiro, EL Bell, KR Mattaini, J Yang… - Nature, 2012 - nature.com
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and
protein acetylation. In the conventional view of mammalian cell metabolism, AcCoA is …

[PDF][PDF] In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation

PA Gameiro, J Yang, AM Metelo, R Pérez-Carro… - Cell metabolism, 2013 - cell.com
Hypoxic and VHL-deficient cells use glutamine to generate citrate and lipids through
reductive carboxylation (RC) of α-ketoglutarate. To gain insights into the role of HIF and the …

Homogeneous, low‐volume, efficient, and sensitive quantitation of circulating exosomal PD‐L1 for cancer diagnosis and immunotherapy response prediction

M Huang, J Yang, T Wang, J Song, J Xia… - Angewandte …, 2020 - Wiley Online Library
Immunotherapy has revolutionized cancer treatment, but its efficacy is severely hindered by
the lack of effective predictors. Herein, we developed a homogeneous, low‐volume, efficient, …

Removal of chromium (VI) from water by porous carbon derived from corn straw: Influencing factors, regeneration and mechanism

H Ma, J Yang, X Gao, Z Liu, X Liu, Z Xu - Journal of Hazardous Materials, 2019 - Elsevier
Porous carbon is one of the most widely used materials to remove Cr(VI) from polluted water.
Here we reported one efficient porous carbon material prepared from corn straw. The …

circ_KIAA1429 accelerates hepatocellular carcinoma advancement through the mechanism of m6A-YTHDF3-Zeb1

M Wang, Y Yang, J Yang, J Yang, S Han - Life sciences, 2020 - Elsevier
Aims Hepatocellular carcinoma (HCC), one of the most common cancer, causes the fourth
cancer-related deaths around the world. N6-methyladenosine (m 6 A) has been reported to …

L2-L state estimation for continuous stochastic delayed neural networks via memory event-triggering strategy

J Yang, L Ma, Y Chen, X Yi - International Journal of Systems …, 2022 - Taylor & Francis
In this paper, we study the memory event-triggering L 2 - L ∞ state estimation for a type of
continuous stochastic neural networks (NNs) subject to time-varying delays. The information of …

Solubilization properties of polycyclic aromatic hydrocarbons by saponin, a plant-derived biosurfactant

W Zhou, J Yang, L Lou, L Zhu - Environmental Pollution, 2011 - Elsevier
The enhanced solubilization of polycyclic aromatic hydrocarbons (PAHs) by saponin, a plant-derived
non-ionic biosurfactant, was investigated. The results indicated that the …

Structure and function of a potent lipopolysaccharide-binding antimicrobial and anti-inflammatory peptide

L Wei, J Yang, X He, G Mo, J Hong, X Yan… - Journal of Medicinal …, 2013 - ACS Publications
Antimicrobial peptides (AMPs) play pivotal roles in the innate defense of vertebrates. A
novel AMP (cathelicidin-PY) has been identified from the skin secretions of the frog Paa …

[HTML][HTML] Modified nano-graphite/Fe3O4 composite as efficient adsorbent for the removal of methyl violet from aqueous solution

C Li, Y Dong, J Yang, Y Li, C Huang - Journal of Molecular Liquids, 2014 - Elsevier
Nano-graphite/Fe 3 O 4 composite (NG/FC) synthesized through deposition–precipitation
method, was developed for the removal of methyl violet (MV) from aqueous solution. The …

Self-assembled DNA dendrimer nanoparticle for efficient delivery of immunostimulatory CpG motifs

Y Qu, J Yang, P Zhan, S Liu, K Zhang… - … Applied Materials & …, 2017 - ACS Publications
Dendrimer-like DNA nanostructures have attractive properties such as mechanical stability,
highly branched nanostructure, customized sizes, and biocompatibility. In this study, we …