Background: Allergic rhinitis (AR) is a disease in which T-helper (Th) 2 response is predominant
and its pathogenic mechanism is still poorly understood. Aim: To evaluate the possible …

BACKGROUND: Nitric oxide (NO) has contradictory roles in the pathophysiology of allergic
inflammation in both allergic rhinitis (AR) and asthma. Small amounts of NO produced by …

Objective Heparin-binding epidermal growth factor (HB-EGF) has pleiotropic biological
functions in the female reproductive tract. HB-EGF has a function in the menstruation cycle, …

Aim: To study the efficacy of pirfenidone for prevention of postoperative adhesion formation
in an adhesion rat model. Materials and Methods: Eighteen female Wistar rats were …

Aberrant activation of the JAK/STAT pathway may predispose to malignancy as a consequence
of the deregulation of cell proliferation, differentiation or apoptosis such as in cancer of …

Background. Increased vascularity due to neo-angiogenesis is an essential part of airway
remodelling. Vascular endothelial growth factor (VEGF), CD34 and von Willebrand’s factor (…

Background. Seasonal allergic rhinitis (SAR) is characterized by a helper T (Th) 2 cell-mediated
immune response at the target site. There is a relative Th1 and/or regulatory T (Treg) …

OBJECTIVE: To compare the mechanism of action of raloxifene and gosereline induced
shrinkage of leiomyomas via estrogen receptor, progesterone receptor, bcl-2 and p53 …

Abdominal surgery is linked with peritoneal adhesions. We investigated that the anti‐fibrotic
agent pirfenidone (PFD) has immune modulating activities and evaluated its effects on the …

… Author links open overlay panel Sevinc Inan a , Gulsen Giray a , H Seda Vatansever a ,
Kemal Ozbilgin a , N Kemal Kuscu b , Sevil Sayhan c …