[HTML][HTML] Mitochondrial abnormalities in patients with primary open-angle glaucoma
KK Abu-Amero, J Morales… - … ophthalmology & visual …, 2006 - arvojournals.org
purpose. Primary open-angle glaucoma (POAG) is the second most common cause of
blindness. It has been linked to mutations in the myocilin (MYOC) and optineurin (OPTN) genes, …
blindness. It has been linked to mutations in the myocilin (MYOC) and optineurin (OPTN) genes, …
[HTML][HTML] Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease
…, DM Kirby, R Salemi, KK Abu-Amero… - The American Journal of …, 2008 - cell.com
Complex I (NADH:ubiquinone oxidoreductase) is the first and largest multimeric complex of
the mitochondrial respiratory chain. Human complex I comprises seven subunits encoded by …
the mitochondrial respiratory chain. Human complex I comprises seven subunits encoded by …
Eurasian and African mitochondrial DNA influences in the Saudi Arabian population
KK Abu-Amero, AM González, JM Larruga… - BMC evolutionary …, 2007 - Springer
Background Genetic studies of the Arabian Peninsula are scarce even though the region
was the center of ancient trade routes and empires and may have been the southern corridor …
was the center of ancient trade routes and empires and may have been the southern corridor …
[PDF][PDF] Mutations in FBXL4 cause mitochondrial encephalopathy and a disorder of mitochondrial DNA maintenance
Nuclear genetic disorders causing mitochondrial DNA (mtDNA) depletion are clinically and
genetically heterogeneous, and the molecular etiology remains undiagnosed in the majority …
genetically heterogeneous, and the molecular etiology remains undiagnosed in the majority …
Resveratrol and ophthalmic diseases
KK Abu-Amero, AA Kondkar, KV Chalam - Nutrients, 2016 - mdpi.com
Resveratrol, a naturally occurring plant polyphenol found in grapes, is the principal biologically
active component in red wine. Clinical studies have shown that resveratrol due to its …
active component in red wine. Clinical studies have shown that resveratrol due to its …
A common variant near TGFBR3 is associated with primary open angle glaucoma
…, S Sripriya, N Fuse, KK Abu-Amero… - Human molecular …, 2015 - academic.oup.com
Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex
disease with a significant genetic contribution. We performed Exome Array (Illumina) …
disease with a significant genetic contribution. We performed Exome Array (Illumina) …
A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome
…, MC Lee, KP Burdon, YS Astakhov, KK Abu-Amero… - Nature …, 2015 - nature.com
Exfoliation syndrome (XFS) is the most common recognizable cause of open-angle
glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome-wide …
glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome-wide …
Saudi Arabian Y-Chromosome diversity and its relationship with nearby regions
KK Abu-Amero, A Hellani, AM González, JM Larruga… - BMC genetics, 2009 - Springer
Background Human origins and migration models proposing the Horn of Africa as a
prehistoric exit route to Asia have stimulated molecular genetic studies in the region using …
prehistoric exit route to Asia have stimulated molecular genetic studies in the region using …
[HTML][HTML] Genetics of keratoconus: where do we stand?
KK Abu-Amero, AM Al-Muammar… - Journal of …, 2014 - hindawi.com
Keratoconus is a progressive thinning and anterior protrusion of the cornea that results in
steepening and distortion of the cornea, altered refractive powers, and reduced vision. …
steepening and distortion of the cornea, altered refractive powers, and reduced vision. …
Mitochondrial DNA structure in the Arabian Peninsula
KK Abu-Amero, JM Larruga, VM Cabrera… - BMC evolutionary …, 2008 - Springer
Background Two potential migratory routes followed by modern humans to colonize Eurasia
from Africa have been proposed. These are the two natural passageways that connect both …
from Africa have been proposed. These are the two natural passageways that connect both …