The gut microbiota benefits humans via short-chain fatty acid (SCFA) production from
carbohydrate fermentation, and deficiency in SCFA production is associated with type 2 diabetes …

The gut microbiota has been linked with chronic diseases such as obesity in humans.
However, the demonstration of causality between constituents of the microbiota and specific …

Structural disruption of gut microbiota and associated inflammation are considered
important etiological factors in high fat diet (HFD)-induced metabolic syndrome (MS). Three …

Smac mimetics induce apoptosis synergistically with TNF-α by triggering the formation of a
caspase-8-activating complex containing receptor interacting protein kinase-1 (RIPK1). …

The gut microbiota is hypothesized to have a critical role in metabolic diseases, including
type 2 diabetes (T2D). A traditional Chinese herbal formula, Gegen Qinlian Decoction (GQD), …

We previously showed that leptin inhibits bone formation by an undefined mechanism. Here,
we show that hypothalamic leptin-dependent antiosteogenic and anorexigenic networks …

Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome)
and individual variations in the microbiome influence host health, may be …

Both genetic variations and diet-disrupted gut microbiota can predispose animals to metabolic
syndromes (MS). This study assessed the relative contributions of host genetics and diet …

Because adult lung tissue has limited regeneration capacity, lung transplantation is the primary
therapy for severely damaged lungs. To explore whether lung tissue can be regenerated …

Despite a long-suspected role in the development of human colorectal cancer (CRC), the
composition of gut microbiota in CRC patients has not been adequately described. In this study…