User profiles for Maha H. Abdulla
 | Maha-Hamadien AbdullaAssociate Professor, Department of surgery, King Saud University, Riyadh. Saudi Arabia Verified email at ksu.edu.sa Cited by 2056 |
[PDF][PDF] Bowel function and its associated variables in Saudi adults
Objectives: To study bowel patterns (function/habits) and its associated variables in an adult
Saudi population. Methods: In a cross sectional study, a 21-item questionnaire on bowel …
Saudi population. Methods: In a cross sectional study, a 21-item questionnaire on bowel …
[HTML][HTML] Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor
Background Schistosomiasis is a chronic, debilitating parasitic disease infecting more than
200 million people and is second only to malaria in terms of public health importance. Due to …
200 million people and is second only to malaria in terms of public health importance. Due to …
[HTML][HTML] Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening
MH Abdulla, DS Ruelas, B Wolff… - PLoS neglected …, 2009 - journals.plos.org
Background Praziquantel (PZQ) is the only widely available drug to treat schistosomiasis.
Given the potential for drug resistance, it is prudent to search for novel therapeutics. …
Given the potential for drug resistance, it is prudent to search for novel therapeutics. …
[HTML][HTML] Increased expression of tumor necrosis factor-α is associated with advanced colorectal cancer stages
…, R Boushey, JH Mckerrow, MH Abdulla - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To detect the expression of tumor necrosis factor-α (TNF-α) in colorectal cancer (CRC)
cells among Saudi patients, and correlate its expression with clinical stages of cancer. …
cells among Saudi patients, and correlate its expression with clinical stages of cancer. …
[HTML][HTML] RNA Interference of Trypanosoma brucei Cathepsin B and L Affects Disease Progression in a Mouse Model
MH Abdulla, T O'Brien, ZB Mackey… - PLoS neglected …, 2008 - journals.plos.org
We investigated the roles played by the cysteine proteases cathepsin B and cathepsin L (brucipain)
in the pathogenesis of Trypansoma brucei brucei in both an in vivo mouse model …
in the pathogenesis of Trypansoma brucei brucei in both an in vivo mouse model …
Bowel function and its associated variables in Saudi adults a population based study
…, AS Nouf H, AQ Xena A, S Shaffi A, A Maha H… - 2012 - pesquisa.bvsalud.org
To study bowel patterns [function/habits] and its associated variables in an adult Saudi
population. In a cross sectional study, a 21-item questionnaire on bowel function [habits and …
population. In a cross sectional study, a 21-item questionnaire on bowel function [habits and …
[HTML][HTML] Bioactivities of the green synthesized silver nanoparticles reduced using Allium cepa L aqueous extracts induced apoptosis in colorectal cancer cell lines
…, AT Ali, YAH Hassan, MH Abdulla - Journal of …, 2022 - hindawi.com
Allium cepa L (A. cepa) extract is frequently used as an adjuvant food in cancer treatment.
We hypothesized that it contains a source of anticancer activity. There is a need to synthesize …
We hypothesized that it contains a source of anticancer activity. There is a need to synthesize …
Urolithin A induces cell cycle arrest and apoptosis by inhibiting Bcl-2, increasing p53-p21 proteins and reactive oxygen species production in colorectal cancer cells
…, K Al-Khayal, TB Traiki, MH Abdulla - Cell Stress and …, 2021 - Springer
… We used different concentrations of UA (25, 50, and 100 μM) at 24 h and 48 h. HT29
treated with UA induced significant late apoptosis (P < 0.001) at 24 h (13.3%) and 48 h (14.35%) …
treated with UA induced significant late apoptosis (P < 0.001) at 24 h (13.3%) and 48 h (14.35%) …
[HTML][HTML] Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling
…, A Haseeb, J McKerrow, R Ahmad, MH Abdulla - Cancer Cell …, 2020 - Springer
… Cells were transfected for 48 h at 37 C and then HM (100 μg/ml) was added for a further
24 h of incubation. TLR4 siRNA-transfected cells were harvested for TLR4 expression …
24 h of incubation. TLR4 siRNA-transfected cells were harvested for TLR4 expression …
[HTML][HTML] Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs
MH Abdulla, KC Lim, JH McKerrow… - PLoS neglected tropical …, 2011 - journals.plos.org
Background Eggs deposited in the liver of the mammalian host by the blood fluke parasite,
Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response …
Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response …
