A molecular test for Alzheimer's disease could lead to better treatment and therapies. We
found 18 signaling proteins in blood plasma that can be used to classify blinded samples from …

Context The ability to identify and quantify brain β-amyloid could increase the accuracy of a
clinical diagnosis of Alzheimer disease. Objective To determine if florbetapir F 18 positron …

A sensitive immunohistochemical method for phosphorylated α-synuclein was used to stain
sets of sections of spinal cord and tissue from 41 different sites in the bodies of 92 subjects, …

Background Results of previous studies have shown associations between PET imaging of
amyloid plaques and amyloid-β pathology measured at autopsy. However, these studies …

The two current major staging systems in use for Lewy body disorders fail to classify up to 50%
of subjects. Both systems do not allow for large numbers of subjects who have Lewy-type …

Background The APOE ε4 allele is associated with the risk of late-onset Alzheimer's disease.
The age at which memory decline diverges among persons who are homozygous for the …

Our purpose was to characterize a state of mild cognitive impairment (MCI) in Parkinson's
disease (PD) (PD‐MCI) that would be analogous to the MCI that is posited as a precursor of …

Background Laboratory evidence of cholesterol-induced production of amyloid β as a
putative neurotoxin precipitating Alzheimer disease, along with epidemiological evidence, …

… Professor Osama Sabri and Professor Marwan Sabbagh had full access to all the data in
the study and take responsibility for the integrity of the data and the accuracy of the data …

Objectives: Determine diagnostic accuracy of a clinical diagnosis of Parkinson disease (PD)
using neuropathologic diagnosis as the gold standard. Methods: Data from the Arizona …