Role of excipients in successful development of self-emulsifying/microemulsifying drug delivery system (SEDDS/SMEDDS)

…, A Hussain, MS Hussain, MA Mirza… - Drug development …, 2013 - Taylor & Francis
The oral delivery of hydrophobic drug presents a major challenge because of the low aqueous
solubility of such compounds. Self-emulsifying/microemulsifying drug delivery system (…

Ambient air quality in the holy city of Makkah: A source apportionment with elemental enrichment factors (EFs) and factor analysis (PMF)

…, A Siddique, DO Carpenter, MM Hussain… - Environmental …, 2018 - Elsevier
Air pollution remains a major global public health and environmental issue. We assessed
the levels of PM 2.5 and delineated the major sources in Makkah, Saudi Arabia. Fine …

Multipathways human health risk assessment of trihalomethane exposure through drinking water

A Siddique, S Saied, M Mumtaz, MM Hussain… - Ecotoxicology and …, 2015 - Elsevier
Life-time human health risk of cancer attributed to trihalomethanes in drinking water in an
urban-industrialized area of Karachi (Pakistan) was conducted through multiple pathways of …

Induction of CYP1A1 and CYP1B1 by benzo (k) fluoranthene and benzo (a) pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH …

DC Spink, SJ Wu, BC Spink, MM Hussain… - Toxicology and applied …, 2008 - Elsevier
The interactions of polycyclic aromatic hydrocarbons (PAH) and cytochromes P450 (CYP)
are complex; PAHs are enzyme inducers, substrates, and inhibitors. In T-47D breast cancer …

Effect of supplementing exogenous protease in low protein poultry by-product meal based diets on growth performance and nutrient digestibility in broilers

…, H Nawaz, M Shahid, M Athar, M Hussain - Animal Feed Science …, 2017 - Elsevier
A 3 × 2 × 2 experiment using 3 levels (0, 30 and 60 g/kg) of poultry by-product meal (PBM),
two levels (180 and 190 g/kg) of crude protein (CP) and two levels of exogenous protease (…

Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin

BC Spink, MM Hussain, BH Katz, L Eisele… - Biochemical …, 2003 - Elsevier
The aryl hydrocarbon receptor (AhR), when activated by exogenous ligands such as 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD), regulates expression of several phase I and phase II …

[PDF][PDF] Chemical characterization and source apportionment of PM2. 5 in Rabigh, Saudi Arabia

…, HA Khwaja, A Siddique, MM Hussain… - Aerosol and Air …, 2016 - escholarship.org
The present study describes the measurement, chemical characterization and delineation of
sources of fine particulate matter (PM2. 5) in Rabigh, Saudi Arabia. The 24-h PM2. 5 was …

Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo [a] pyrene is diminished by arsenite

DC Spink, BH Katz, MM Hussain, BC Spink… - Drug metabolism and …, 2002 - ASPET
Polycyclic aromatic hydrocarbons (PAHs) and metals are often environmental cocontaminants,
yet there have been relatively few studies of combined effects of PAHs and metals on …

Assessing the association between fine particulate matter (PM2. 5) constituents and cardiovascular diseases in a mega-city of Pakistan

Y Lu, S Lin, Z Fatmi, D Malashock, MM Hussain… - Environmental …, 2019 - Elsevier
Concerning PM 2.5 concentrations, rapid industrialization, along with increase in cardiovascular
disease (CVD) were recorded in Pakistan, especially in urban areas. The degree to …

Fine particulate matter and its chemical constituents' levels: A troubling environmental and human health situation in Karachi, Pakistan

…, A Siddique, K Khan, J Zeb, MM Hussain… - Science of The Total …, 2023 - Elsevier
Like many urban centers in developing countries, the effect of air pollution in Karachi is
understudied. The goal of this study was to determine the chemical characterization, temporal …