Abnormal protein aggregation in the brain is linked to the pathogenesis of neurodegenerative
diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Recent …

Background: Comprehensive global data on the health effects of indoor air pollutants are
lacking. There are few large population-based multi–air pollutant health assessments. Further, …

Peroxisome proliferator-activated receptor (PPAR) agonists are used as adjunct therapy in
the treatment of diabetes mellitus. Fibrates, including fenofibrate, gemfibrozil, benzafibrate, …

Diabetes constitutes a major health challenge. Since cardiovascular complications are common
in diabetic patients this will further increase the overall burden of disease. Furthermore, …

Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after
Alzheimer’s disease (AD). The formation of the cytoplasmic inclusions named “Lewy bodies” in …

Prophylactic administration of reversible acetylcholinesterase (AChE) inhibitors before
exposure to organophosphorus compounds (OPCs) can reduce OPC‐induced mortality. …

In search for more efficacious reactivators of acetylcholinesterase (AChE) inhibited by
organophosphorus compounds, experimental K‐oximes have been synthesized which show good …

Reversible acetylcholinesterase (AChE) inhibitors can protect against the lethal effects of
irreversible organophosphorus AChE inhibitors (OPCs), when administered before OPC …

In the United Arab Emirates (UAE), overall diabetes prevalence in adult population is around
20%. Along with, or instead of oral hypoglycemic drugs and insulin, some patients use …

Weak and reversible inhibitors of cholinesterase, when co‐administered in large doses, can
act in a protective manner against more potent inhibitors such as organophosphates. The …