User profiles for Mohammad A. Alfhili
Mohammad A. AlfhiliAssistant Professor, King Saud University Verified email at ksu.edu.sa Cited by 656 |
[HTML][HTML] Triclosan: an update on biochemical and molecular mechanisms
MA Alfhili, MH Lee - Oxidative medicine and cellular longevity, 2019 - hindawi.com
Triclosan (TCS) is a synthetic, chlorinated phenolic antimicrobial agent commonly used in
commercial and healthcare products. Items made with TCS include soaps, deodorants, …
commercial and healthcare products. Items made with TCS include soaps, deodorants, …
[HTML][HTML] Molecular mechanisms and pathophysiological significance of eryptosis
Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …
[HTML][HTML] Antioxidant, Anti-Proliferative Activity and Chemical Fingerprinting of Centaurea calcitrapa against Breast Cancer Cells and Molecular Docking of Caspase-3
Centaurea calcitrapa has been intensively utilized in ethnomedicinal practices as a natural
therapeutic recipe to cure various ailments. The current study aimed to chemically …
therapeutic recipe to cure various ailments. The current study aimed to chemically …
[HTML][HTML] Stimulation of hemolysis and eryptosis by α-Mangostin through Rac1 GTPase and oxidative injury in human red blood cells
Background: Chemotherapy-related anemia is prevalent in up to 75% of patients, which
may arise due to hemolysis and eryptosis. Alpha-mangostin (α-MG) is a polyphenolic …
may arise due to hemolysis and eryptosis. Alpha-mangostin (α-MG) is a polyphenolic …
Metabolic exhaustion and casein kinase 1α drive deguelin-induced premature red blood cell death
MA Alfhili, J Alsughayyir - Xenobiotica, 2023 - Taylor & Francis
Deguelin (DGN), a retinoid isolated from many plants, exhibits a potent anticancer activity
against a wide spectrum of tumour cells. There is a dearth of evidence, however, regarding the …
against a wide spectrum of tumour cells. There is a dearth of evidence, however, regarding the …
[HTML][HTML] Lauric acid, a dietary saturated medium-chain fatty acid, elicits calcium-dependent eryptosis
MA Alfhili, GS Aljuraiban - Cells, 2021 - mdpi.com
Cardiovascular diseases (CVD) are a leading cause of mortality worldwide, and dietary
habits represent a major risk factor for dyslipidemia; a hallmark of CVD. Saturated fatty acids …
habits represent a major risk factor for dyslipidemia; a hallmark of CVD. Saturated fatty acids …
Disruption of erythrocyte membrane asymmetry by triclosan is preceded by calcium dysregulation and p38 MAPK and RIP1 stimulation
MA Alfhili, DA Weidner, MH Lee - Chemosphere, 2019 - Elsevier
Triclosan (TCS) is a broad-spectrum antimicrobial used in personal care products, household
items, and medical devices. Owing to its apoptotic potential against tumor cells, TCS has …
items, and medical devices. Owing to its apoptotic potential against tumor cells, TCS has …
Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid‐induced hyperuricemia rats
Background Recent studies indicate hyperuricemia as an aggravating factor for kidney
diseases progression. Basic research for novel agents to reduce hyperuricemia and kidney …
diseases progression. Basic research for novel agents to reduce hyperuricemia and kidney …
[HTML][HTML] Triclosan Disrupts SKN-1/Nrf2-Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells
…, Y Choi, DS Cha, P Zhang, SM Choi, MA Alfhili… - Scientific reports, 2017 - nature.com
Triclosan (TCS), an antimicrobial chemical with potential endocrine-disrupting properties,
may pose a risk to early embryonic development and cellular homeostasis during adulthood. …
may pose a risk to early embryonic development and cellular homeostasis during adulthood. …
[HTML][HTML] Monocyte–Lymphocyte Ratio and Dysglycemia: A Retrospective, Cross-Sectional Study of the Saudi Population
Background: Abnormalities in fasting blood glucose (FBG) resulting in hypoglycemia (OG),
impaired fasting glycemia (IFG), or hyperglycemia (HG) arise from disordered metabolic …
impaired fasting glycemia (IFG), or hyperglycemia (HG) arise from disordered metabolic …