Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling

…, M Al-Shraim, AF El-Kott, MSA Zaki, MA Dallak… - Basic research in …, 2018 - Springer
The molecular mechanisms through which ghrelin exerts its cardioprotective effects during
cardiac remodeling post-myocardial infarction (MI) are poorly understood. The aim of this …

The ameliorative effect of kaempferol against CdCl2- mediated renal damage entails activation of Nrf2 and inhibition of NF-kB

…, EH Ibrahim, MS Mahmoud, MA Dallak… - … Science and Pollution …, 2022 - Springer
This study evaluated the nephroprotective effect of kaempferol against cadmium chloride (CdCl
2 ) -induced nephropathy in rats. It also investigated if activation of Nrf2 is a common …

[HTML][HTML] Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats

MM Dallak, DP Mikhailidis, MA Haidara… - The open …, 2008 - ncbi.nlm.nih.gov
Aim: To investigate the possible role of oxidative stress as a common mediator of apoptosis
and cardiac damage in diabetes. Materials and Methods: This experimental work was …

[HTML][HTML] Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/PKC/JNK pathway

MA Dallak - Biomedicine & Pharmacotherapy, 2018 - Elsevier
This study investigated the molecular effects of acylated (AG) and unacylated ghrelin (UAG)
or their combination on hepatic lipogenesis pathways and DAG/PKC/JNK signaling in the …

Khat (Catha edulis) extract increases oxidative stress parameters and impairs renal and hepatic functions in rats

FH Al-Hashem, I Bin-Jaliah, MA Dallak… - Bahrain med …, 2011 - platform.almanhal.com
Background: The habit of khat chewing represents a major socio-economic problem in many
countries but research into its hepato-renal toxic effects has produced contradictory results. …

Derangement of hemopoiesis and hematological indices in Khat (Catha edulis)-treated rats

I Bin-Jaliah, MA Dallak, FH Al-Hashem… - African Journal of …, 2014 - ajol.info
The purpose of this study was to identify the sub-acute toxic effects of Khat (Catha edulis) on
hemopoiesis and hematological indices of white albino rats. Two groups, each of 10 rats, …

[HTML][HTML] Acute exposure to Catha edulis depresses contractility and induces myocardial infarction in spontaneously contracting, isolated rabbit's heart

FH Al-Hashem, MA Dallak, LO Nwoye… - Saudi journal of …, 2012 - Elsevier
Khat chewing is a recreational habit known to pose major socio-economic and medical
problems in countries of Southern Arabia and the Horn of Africa. Among other adverse health …

Thrombocytopenia in patients with chronic hepatitis C: a possible role of HCV on platelet progenitor cell maturation

…, FM Attia, MI Mandour, MA Haidara, MM Dallak… - …, 2010 - journals.sagepub.com
A total of 30 patients with chronic hepatitis C (HCV) thrombocytopenia (TP) and 20 healthy
controls were studied. Both groups were subjected to complete medical history, clinical …

The influence of pulmonary receptors on respiratory drive in a rabbit model of pulmonary emphysema

MA Dallak, LJL Pirie, A Davies - Respiratory physiology & neurobiology, 2007 - Elsevier
We have observed that pulmonary rapidly adapting receptor activity is greater in emphysematous
rats than in controls. Pulmonary receptor activity, if modified by lung disease, may …

Exercise augments the modulatory effects of vitamin E on pre-diabetes-induced aortopathy: a potential role of adiponectin

MA Dallak, B Al-Ani, AO El Karib… - … of physiology and …, 2020 - Taylor & Francis
Background: We tested the hypothesis that vitamin E may protect against pre-diabetes-induced
aortic injury (aortopathy), and exercise can augment the action of vitamin E. Material and …