Cell signaling pathways, responsible for maintaining a balance between cell proliferation
and death, have emerged as rational targets for the management of cancer. Emerging data …

Chemoprevention has come of age as an effective cancer control modality; however, the
search for novel agent(s) for the armamentarium of cancer chemoprevention continues. We …

In the Western world, an average of 250mg per day of triterpenes (member of phytosterol
family), largely derived from vegetable oils, cereals, fruits and vegetables is consumed by …

Since ancient times, natural products have been used as remedies to treat human diseases.
Lupeol, a phytosterol and triterpene, is widely found in edible fruits, and vegetables. …

There is increasing evidence that a variety of cancers arise from transformation of normal
stem cells to cancer stem cells (CSCs). CSCs are thought to sustain cancer progression, …

Coronavirus disease of 2019 (COVID-19) has emerged as a global health threat. Unfortunately,
there are very limited approved drugs available with established efficacy against the …

Chemoprevention has become an effective cancer control modality; however, the search for
novel agent (s) for the armamentarium of cancer chemoprevention continues. We argue that …

c-Kit, a receptor tyrosine kinase, is involved in intracellular signaling, and the mutated form
of c-Kit plays a crucial role in occurrence of some cancers. The function of c-Kit has led to the …

Delphinidin, a major anthocyanidin present in many pigmented fruits and vegetables, possesses
antioxidant, anti-inflammatory, and antiangiogenic properties. In this study, we provide …

Accumulating evidence suggests that codeletion of the tumor suppressor genes Pten and
p53 plays a crucial role in the development of castration-resistant prostate cancer in vivo. …