Phosphatidylinositol 3′-kinase (PI3K) is a key player in cell-growth signaling in a number of
lymphoid malignancies, but its role in diffuse large B-cell lymphoma (DLBCL) has not been …

Primary effusion lymphoma (PEL) is an incurable, aggressive B-cell malignancy that develops
rapid resistance to conventional chemotherapy. In efforts to identify novel approaches to …

We provide evidence that curcumin, a natural compound isolated from rhizomes of plant
Curcuma longa, induces apoptosis in several Burkitt's lymphoma cell lines expressing Bax …

Objective: To document the incidence and role of p53 and DNA mismatch repair proteins in
colorectal carcinomas, and to evaluate the relative frequency of major molecular pathways in …

Objective To evaluate the overall incidence of microsatellite instability (MSI), hereditary non
polyposis colorectal cancer, and tumor supressor gene (TP53) mutations in Saudi colorectal …

Several messenger ribonucleic acid (mRNA) and inactivated COVID-19 vaccines are available
to the global population as of 2022. The acceptance of the COVID-19 vaccine will play a …

Active breast cancer-associated fibroblasts (CAFs), the most influential cells in breast tumor
microenvironment, express/secrete high levels of the proinvasive/metastatic interleukin-6 (IL-…

The last four decades have seen significant increase in the incidence of non-Hodgkin
lymphoma (NHL) as a possible result of increasing environmental carcinogens exposure. Based …

Background Pds5 is an abundant HEAT-repeat-containing protein that binds to cohesin and
mediates sister chromatid cohesion. In vertebrates, Pds5A and Pds5B are known to protect …

Glioblastoma multiforme (GBM) is the most prevalent, highly malignant, invasive and difficult-to-treat
primary brain tumor in adults. At the genetic level, it is characterized by a high …